Chromosome changes in rat embryo cell lines transformed by temperature-sensitive mutants and sheared DNA of herpes simplex virus

The chromosomes of six rat embryo cell lines transformed with herpes simplex virus (HSV) temperature-sensitive (ts) mutants were examined at different passages of in vitro cultivation. Two cell lines were predominantly diploid, one cell line was hyperdiploid, one cell line was pseudodiploid, and two...

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Veröffentlicht in:	Cancer genetics and cytogenetics 1982-01, Vol.7 (4), p.313-326
Hauptverfasser:	Nachtigal, Maurice, Nachtigal, Sidonia, Lungeanu, Agripina, Macnab, Joan C.M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Line Cell Transformation, Neoplastic Cell Transformation, Viral Chromosomes - physiology DNA, Viral - genetics Embryo, Mammalian herpes simplex virus Karyotyping Mutation Neoplasms, Experimental - genetics Neoplasms, Experimental - microbiology Rats Simplexvirus - genetics Temperature
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