Ketanserin : a review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in hypertension and peripheral vascular disease

Ketanserin is a 5-HT2 receptor antagonist without partial agonist properties which also possesses weak alpha 1-adrenoceptor antagonistic activity, which may explain its antihypertensive mechanism of action in patients with essential hypertension. It also inhibits the effects of serotonin on platelet...

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Veröffentlicht in:	Drugs (New York, N.Y.) N.Y.), 1990-12, Vol.40 (6), p.903-949
Hauptverfasser:	BROGDEN, R. N, SORKIN, E. M
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antihypertensive agents Biological and medical sciences Cardiovascular system Humans Hypertension - drug therapy Hypertension - physiopathology Ketanserin - pharmacokinetics Ketanserin - pharmacology Ketanserin - therapeutic use Medical sciences Pharmacology. Drug treatments Vascular Diseases - drug therapy Vascular Diseases - physiopathology
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