Transdermal Oxymorphone Formulation Development and Methods for Evaluating Flux and Lag Times for Two Skin Permeation-Enhancing Vehicles

Oxymorphone is a candidate for transdermal delivery since it is a very potent analgesic, is not very effective orally, and has a short duration of action. In developing a transdermal delivery system, two criteria that were considered important were achieving adequate flux and minimizing the lag time...

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