Suppressive effect of E-64c on ischemic degradation of cerebral proteins following occlusion of the middle cerebral artery in rats

Microtubule-associated protein 2 (MAP2) levels in the left cerebral hemisphere decreased significantly 3 days after occlusion of the left middle cerebral artery in rats to29 ± 16.3% of control levels. Since MAP2 is one of the substrates of calpain, E-64c, a synthetic calpain inhibitor, was administe...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Brain research 1990-08, Vol.526 (1), p.177-179
Hauptverfasser:	Inuzuka, Takashi, Tamura, Akira, Sato, Shuzo, Kirino, Takaaki, Toyoshima, Itaru, Miyatake, Tadashi
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Calpain Calpain - antagonists & inhibitors Cerebral Arteries Cerebral ischemia E-64c Immunoblotting Ischemic Attack, Transient - drug therapy Ischemic Attack, Transient - metabolism Leucine - analogs & derivatives Leucine - pharmacology Male Microtubule-associated protein 2 Microtubule-Associated Proteins - metabolism Myelin Proteins - metabolism Myelin-Associated Glycoprotein Rats Rats, Inbred Strains
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!