In vitro activity of sparfloxacin (AT-4140, CI-978, PD 131501), a new quinolone antimicrobial agent
In vitro activity of sparfloxacin (AT-4140, CI-978, PD 131501) against clinical bacterial isolates was compared with those of ciprofloxacin and vancomycin or imipenem. Sparfloxacin was more active or equal to ciprofloxacin against most Gram-positive species and against Bacteroides fragilis, and it i...
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| Veröffentlicht in: | Diagnostic microbiology and infectious disease 1990-07, Vol.13 (4), p.345-348 |
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| container_end_page | 348 |
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| container_issue | 4 |
| container_start_page | 345 |
| container_title | Diagnostic microbiology and infectious disease |
| container_volume | 13 |
| creator | Eliopoulos, George M. Klimm, Karin Grayson, M.Lindsay |
| description | In vitro activity of sparfloxacin (AT-4140, CI-978, PD 131501) against clinical bacterial isolates was compared with those of ciprofloxacin and vancomycin or imipenem. Sparfloxacin was more active or equal to ciprofloxacin against most Gram-positive species and against Bacteroides fragilis,
and it inhibited virtually all Enterobacteriaceae
at 1.0 μg/ml or less. |
| doi_str_mv | 10.1016/0732-8893(90)90029-U |
| format | Article |
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and it inhibited virtually all Enterobacteriaceae
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| fulltext | fulltext |
| identifier | ISSN: 0732-8893 |
| ispartof | Diagnostic microbiology and infectious disease, 1990-07, Vol.13 (4), p.345-348 |
| issn | 0732-8893 1879-0070 |
| language | eng |
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| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Anti-Infective Agents - pharmacology Antibacterial agents Antibiotics. Antiinfectious agents. Antiparasitic agents Bacteria - drug effects Biological and medical sciences Ciprofloxacin - pharmacology Fluoroquinolones Humans Imipenem - pharmacology Medical sciences Pharmacology. Drug treatments Vancomycin - pharmacology |
| title | In vitro activity of sparfloxacin (AT-4140, CI-978, PD 131501), a new quinolone antimicrobial agent |
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