Characterization of a hot-melt fluid bed coating process for fine granules

The equipment modifications and process changes necessary to perform hot-melt particle coating in a fluid bed granulator are reviewed. A specific case is presented in which partially hydrogenated cottonseed oil is coated onto fine granules (mean particle size, 77 microns; range, 10-150 microns; one...

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Veröffentlicht in:	Pharmaceutical research 1990-11, Vol.7 (11), p.1119-1126
Hauptverfasser:	JOZWIAKOWSKI, M. J, JONES, D. M, FRANZ, R. M
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Capsules Chemistry, Pharmaceutical Chromatography, High Pressure Liquid Cottonseed Oil Drug Compounding Excipients General pharmacology Medical sciences Microscopy, Electron, Scanning Models, Biological Particle Size Pharmaceutical technology. Pharmaceutical industry Pharmacology. Drug treatments Regression Analysis Technology, Pharmaceutical
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