Reversed-Phase Ion-Pair High-Performance Liquid Chromatographic Determination of Fluoroquinolones in Human Plasma

A simple and sensitive method is described for the determination of fluoroquinolones by HPLC on a C-18 column using fluorescence detection. Using a mobile phase of 25% (v/v) acetonitrile phosphate buffer (pH 2.0), adequate retention and separation among the solutes norfloxacin, amifloxacin, enoxacin...

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Veröffentlicht in:	Journal of pharmaceutical sciences 1990-11, Vol.79 (11), p.988-991
Hauptverfasser:	Nangia, Avinash, Lam, Frederick, Hung, Cheung-Tak
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Infective Agents - blood Anti-Infective Agents - pharmacokinetics Chromatography, High Pressure Liquid Ciprofloxacin - analogs & derivatives Ciprofloxacin - pharmacokinetics Fluoroquinolones Humans Hydrogen-Ion Concentration Indicators and Reagents Male Regression Analysis
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