Microtubule-Based Cell Motility: The Role of Microtubules in Cell Motility and Differentiation

Responses to cytokines include not only lymphocyte differentiation, but growth, chemotaxis, motility, and differentiation of a variety of cells. For example, interleukin-6 has activities that may affect epithelial cells as diverse as hepatocytes and endometrium, and it may also have nerve growth fac...

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Veröffentlicht in:Cancer investigation 1990, Vol.8 (6), p.685-690
Hauptverfasser: Satir, Peter, Goltz, Jason S., Wolkoff, Allan W.
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creator Satir, Peter
Goltz, Jason S.
Wolkoff, Allan W.
description Responses to cytokines include not only lymphocyte differentiation, but growth, chemotaxis, motility, and differentiation of a variety of cells. For example, interleukin-6 has activities that may affect epithelial cells as diverse as hepatocytes and endometrium, and it may also have nerve growth factor-like activity, promoting nerve cell differentiation. In the long term, cellular response depends upon the induction of appropriate transcription factors and gene activation, but the final differentiation pathways, as well as more immediate responses such as cell motility, also require assembly and activity of the cell cytomatrix.
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source MEDLINE; Taylor & Francis Medical Library - CRKN; Taylor & Francis Journals Complete
subjects Animals
Cell Differentiation - physiology
Cell Movement - physiology
cytoskeleton
microtubules
Microtubules - physiology
reviews
title Microtubule-Based Cell Motility: The Role of Microtubules in Cell Motility and Differentiation
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