Comparison of Samples of Human Hair by Two-dimensional Electrophoresis
A two-dimensional polyacrylamide gel electrophoretic procedure has been developed to give a very sensitive method which provides a high degree of discrimination between the proteins of different samples of human hair using a sample of 3 mg. Its use is illustrated by examination of hair samples from...
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| Veröffentlicht in: | Journal - Forensic Science Society 1982-10, Vol.22 (4), p.377-385 |
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| container_end_page | 385 |
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| container_start_page | 377 |
| container_title | Journal - Forensic Science Society |
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| creator | Marshall, R.C. Gillespie, J.M. |
| description | A two-dimensional polyacrylamide gel electrophoretic procedure has been developed to give a very sensitive method which provides a high degree of discrimination between the proteins of different samples of human hair using a sample of 3 mg. Its use is illustrated by examination of hair samples from seven individuals spanning three generations of the one family. Eight areas of variability in the electrophoretic patterns were found each of which corresponds to differences in one or more proteins. In addition to variability in patterns due to genetic variations between individuals, changes caused by cosmetic manipulation and environmental damage to the proteins may also be a useful adjunct for identification. This procedure shows potential for the forensic analysis of small samples, possibly even part of a single fibre, of human hair. |
| doi_str_mv | 10.1016/S0015-7368(82)71515-4 |
| format | Article |
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Its use is illustrated by examination of hair samples from seven individuals spanning three generations of the one family. Eight areas of variability in the electrophoretic patterns were found each of which corresponds to differences in one or more proteins. In addition to variability in patterns due to genetic variations between individuals, changes caused by cosmetic manipulation and environmental damage to the proteins may also be a useful adjunct for identification. This procedure shows potential for the forensic analysis of small samples, possibly even part of a single fibre, of human hair.</description><subject>Adult</subject><subject>Amino Acids - analysis</subject><subject>Child</subject><subject>Electrophoresis, Polyacrylamide Gel</subject><subject>Forensic Medicine</subject><subject>Hair - analysis</subject><subject>Humans</subject><issn>0015-7368</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1982</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkLlOw0AQhrcAhfMRIrlCUBjG9l6uEIqAIEWiSKhXe4zFIttrdhNQ3h6HRLRUc_0zv-YjZFrAbQEFv1sCFCwXFZfXsrwRBRsrekRO_9on5CylDwAOXFQTMhkllaD1KXmahW7Q0afQZ6HJlrobWky7dL7pdJ_NtY-Z2War75A732GffOh1mz22aNcxDO8hYvLpghw3uk14eYjn5O3pcTWb54vX55fZwyK3tOTrnDbSlWANaCM4WnC1QyGh0LWjvOZU8loYaUwt0AjHGLMA1CDYuqqYaHh1Tq72d4cYPjeY1qrzyWLb6h7DJikJJZOUwShke6GNIaWIjRqi73TcqgLUjpn6ZaZ2cJQs1S8zRce96cFgYzp0f1sHYOP8fj_H8csvj1El67G36HwciSgX_D8OP2t9fXI</recordid><startdate>198210</startdate><enddate>198210</enddate><creator>Marshall, R.C.</creator><creator>Gillespie, J.M.</creator><general>Elsevier Ireland Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>198210</creationdate><title>Comparison of Samples of Human Hair by Two-dimensional Electrophoresis</title><author>Marshall, R.C. ; Gillespie, J.M.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c426t-4f8d20cb0ab76ec0d9de7801a9d469648697b8bb97eb7d555c004be0c93357f63</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1982</creationdate><topic>Adult</topic><topic>Amino Acids - analysis</topic><topic>Child</topic><topic>Electrophoresis, Polyacrylamide Gel</topic><topic>Forensic Medicine</topic><topic>Hair - analysis</topic><topic>Humans</topic><toplevel>online_resources</toplevel><creatorcontrib>Marshall, R.C.</creatorcontrib><creatorcontrib>Gillespie, J.M.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal - Forensic Science Society</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Marshall, R.C.</au><au>Gillespie, J.M.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Comparison of Samples of Human Hair by Two-dimensional Electrophoresis</atitle><jtitle>Journal - Forensic Science Society</jtitle><addtitle>J Forensic Sci Soc</addtitle><date>1982-10</date><risdate>1982</risdate><volume>22</volume><issue>4</issue><spage>377</spage><epage>385</epage><pages>377-385</pages><issn>0015-7368</issn><abstract>A two-dimensional polyacrylamide gel electrophoretic procedure has been developed to give a very sensitive method which provides a high degree of discrimination between the proteins of different samples of human hair using a sample of 3 mg. 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| fulltext | fulltext |
| identifier | ISSN: 0015-7368 |
| ispartof | Journal - Forensic Science Society, 1982-10, Vol.22 (4), p.377-385 |
| issn | 0015-7368 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_80258450 |
| source | MEDLINE; Alma/SFX Local Collection |
| subjects | Adult Amino Acids - analysis Child Electrophoresis, Polyacrylamide Gel Forensic Medicine Hair - analysis Humans |
| title | Comparison of Samples of Human Hair by Two-dimensional Electrophoresis |
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