$Comparative studies of heparin cofactor activity toward antithrombin III and heparin cofactor II, and antithrombin III affinity between low molecular weight heparin and unfractionated heparin$

Comparative studies of heparin cofactor activity toward antithrombin III and heparin cofactor II, and antithrombin III affinity between low molecular weight heparin and unfractionated heparin

The accelerating effects of an UF heparin (Novo) and two LMW heparins (Fragmin and PK 10169) on AT III and HC II were investigated in a purified system. The effects of these heparins on APTTs were examined using human plasma. Fractionation of these heparins by affinity column chromatography yielded...

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Veröffentlicht in:	Seminars in thrombosis and hemostasis 1990-10, Vol.16, p.71-76
Hauptverfasser:	SHIMOTORI, T, SAKURAGAWA, N
Format:	Artikel
Sprache:	eng
Schlagworte:	Antithrombin III - drug effects Biological and medical sciences Blood. Blood coagulation. Reticuloendothelial system Factor Xa Inhibitors Heparin - pharmacology Heparin Cofactor II - drug effects Heparin, Low-Molecular-Weight - pharmacology Humans Medical sciences Molecular Weight Partial Thromboplastin Time Pharmacology. Drug treatments Thrombin - antagonists & inhibitors
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