Large and small airway responses to bronchoconstrictors in the guinea pig and ferret

In the isolated, perfused lung lobe of the ferret we evaluated the bronchoconstrictor response of its airways to methacholine and histamine, pharmacologic agents associated with the asthmatic state. The bronchus of excised lobes was cannulated and needle scarifications were made on the pleural surfa...

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Veröffentlicht in:	Lung 1990-12, Vol.168 (5), p.249-257
Hauptverfasser:	Vitkun, S A, Foster, W M, Bergofsky, E H, Poppers, P J
Format:	Artikel
Sprache:	eng
Schlagworte:	Airway Resistance - physiology Animals Bronchoconstriction - drug effects Dose-Response Relationship, Drug Female Ferrets Guinea Pigs Histamine - administration & dosage Histamine - pharmacology Lung - anatomy & histology Lung - drug effects Lung Compliance - physiology Male Methacholine Chloride - administration & dosage Methacholine Chloride - pharmacology
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