Prognostic value of pS2 protein and receptors for epidermal growth factor (EGF-R), Insulin-like growth factor-1 (IGF-1-R) and somatostatin (SS-R) in patients with breast and ovarian cancer

The prognostic value of EGF-R, IGF-1-R and SS-R, and of cytosolic estrogen-regulated pS2 protein, was studied in patients (pts) with primary breast and advanced ovarian cancer. Ovarian cancer tissues were negative for pS2 (by immunoradiometric assay) IGF-1-R and EGF-R contents (by ligand binding ass...

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Veröffentlicht in:	Journal of steroid biochemistry and molecular biology 1990-12, Vol.37 (6), p.815-821
Hauptverfasser:	Foekens, J.A., van Putten, W.L.J., Portengen, H., Rodenburg, C.J., Reubi, J.-C., Berns, P.M.J.J., Henzen-Logmans, S.C., van der Burg, M.E.L., Alexieva-Figusch, J., Klijn, J.G.M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Biomarkers, Tumor breast Breast Neoplasms - diagnosis Breast Neoplasms - metabolism carcinoma epidermal growth factor ErbB Receptors - metabolism Female Gynecology. Andrology. Obstetrics Humans insulin-like growth factor I Insulin-Like Growth Factor I - metabolism Mammary gland diseases Medical sciences Neoplasm Proteins - metabolism Ovarian Neoplasms - diagnosis Ovarian Neoplasms - metabolism ovaries Prognosis Proteins pS2 protein receptors Receptors, Cell Surface - metabolism Receptors, Somatomedin somatostatin Trefoil Factor-1 Tumor Suppressor Proteins Tumors
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