Ergotamine in Plasma and CSF After i.m. and Rectal Administration to Humans

An attempt was made to study the kinetics of penetration of ergotamine across the blood-bran barrier. A single therapeutic dose of ergotamine was given to 18 hospitalized patients; eight patients received 0.5 mg i.m., three patients 4 mg rectally, and seven patients 2 mg rectally. Plasma samples wer...

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Veröffentlicht in:	Cephalalgia 1982-09, Vol.2 (3), p.145-150
Hauptverfasser:	Hovdal, Harald, Syversen, Gaby B., Rosenthaler, Joachim
Format:	Artikel
Sprache:	eng
Schlagworte:	Blood-Brain Barrier CSF concentration ergotamine Ergotamine - administration & dosage Ergotamine - blood Ergotamine - cerebrospinal fluid Humans Injections, Intramuscular Kinetics plasma concentration Radioimmunoassay Suppositories
Online-Zugang:	Volltext
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