Chronic granulomatous disease of childhood presenting as gastric outlet obstruction
A case of chronic granulomatous disease of childhood was first diagnosed when a 20-month-old infant developed gastric outlet obstruction. Because of the unusual clinical presentation and negative gastric mucosal biopsies, the diagnosis was delayed. A subsequent full thickness biopsy of the stomach w...
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| Veröffentlicht in: | The American journal of surgical pathology 1982-10, Vol.6 (7), p.673-676 |
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| container_end_page | 676 |
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| container_issue | 7 |
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| container_title | The American journal of surgical pathology |
| container_volume | 6 |
| creator | Varma, V A Sessions, J T Kahn, L B Lipper, S |
| description | A case of chronic granulomatous disease of childhood was first diagnosed when a 20-month-old infant developed gastric outlet obstruction. Because of the unusual clinical presentation and negative gastric mucosal biopsies, the diagnosis was delayed. A subsequent full thickness biopsy of the stomach wall which led to a correct diagnosis showed a granulomatous infiltrate in the muscularis propria. Characteristic yellow pigment-laden macrophages were seen in the gastric mucosa and pyloric lymph node. Early recognition of this chronic disorder is important not only for proper management but genetic counseling as well. |
| doi_str_mv | 10.1097/00000478-198210000-00009 |
| format | Article |
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Because of the unusual clinical presentation and negative gastric mucosal biopsies, the diagnosis was delayed. A subsequent full thickness biopsy of the stomach wall which led to a correct diagnosis showed a granulomatous infiltrate in the muscularis propria. Characteristic yellow pigment-laden macrophages were seen in the gastric mucosa and pyloric lymph node. Early recognition of this chronic disorder is important not only for proper management but genetic counseling as well.</description><subject>Granulomatous Disease, Chronic - complications</subject><subject>Granulomatous Disease, Chronic - diagnosis</subject><subject>Granulomatous Disease, Chronic - pathology</subject><subject>Humans</subject><subject>Infant</subject><subject>Lymph Nodes - pathology</subject><subject>Male</subject><subject>Pyloric Stenosis - etiology</subject><subject>Stomach - pathology</subject><subject>Stomach Diseases - complications</subject><subject>Stomach Diseases - pathology</subject><issn>0147-5185</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1982</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo9UMtOwzAQ9AFUSuETkHziFvAmjR9HVPGSKnEAzpHjR2uUxMF2Dvw9Di3dw65mtbO7MwhhIHdABLsnc6wZL0DwEmZQzEmcoSWBNStq4PUFuozxixAoOZQLtGDAiaB0id43--AHp_AuyGHqfC-TnyLWLhoZDfYWq73r9N57jcdgohmSG3ZYRryTMYVM9FPqTMK-zXBSyfnhCp1b2UVzfawr9Pn0-LF5KbZvz6-bh22hKiCpUIIqSitWClrLutWaWsg_UaWpMsAYaGGlFoqC5VoDUSVIYzknGmyrgVYrdHvYOwb_PZmYmt5FZbpODiaLaDgp11lwnQf5YVAFH2MwthmD62X4aYA0s4fNv4fNycO_lsjUm-ONqe2NPhGPBla_cvlweg</recordid><startdate>198210</startdate><enddate>198210</enddate><creator>Varma, V A</creator><creator>Sessions, J T</creator><creator>Kahn, L B</creator><creator>Lipper, S</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>198210</creationdate><title>Chronic granulomatous disease of childhood presenting as gastric outlet obstruction</title><author>Varma, V A ; Sessions, J T ; Kahn, L B ; Lipper, S</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c310t-c96c66372965a5bdd6f19666cd6ce1771d9fad9c61f8dd10c21aef880d1fbd163</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1982</creationdate><topic>Granulomatous Disease, Chronic - complications</topic><topic>Granulomatous Disease, Chronic - diagnosis</topic><topic>Granulomatous Disease, Chronic - pathology</topic><topic>Humans</topic><topic>Infant</topic><topic>Lymph Nodes - pathology</topic><topic>Male</topic><topic>Pyloric Stenosis - etiology</topic><topic>Stomach - pathology</topic><topic>Stomach Diseases - complications</topic><topic>Stomach Diseases - pathology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Varma, V A</creatorcontrib><creatorcontrib>Sessions, J T</creatorcontrib><creatorcontrib>Kahn, L B</creatorcontrib><creatorcontrib>Lipper, S</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>The American journal of surgical pathology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Varma, V A</au><au>Sessions, J T</au><au>Kahn, L B</au><au>Lipper, S</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Chronic granulomatous disease of childhood presenting as gastric outlet obstruction</atitle><jtitle>The American journal of surgical pathology</jtitle><addtitle>Am J Surg Pathol</addtitle><date>1982-10</date><risdate>1982</risdate><volume>6</volume><issue>7</issue><spage>673</spage><epage>676</epage><pages>673-676</pages><issn>0147-5185</issn><abstract>A case of chronic granulomatous disease of childhood was first diagnosed when a 20-month-old infant developed gastric outlet obstruction. Because of the unusual clinical presentation and negative gastric mucosal biopsies, the diagnosis was delayed. A subsequent full thickness biopsy of the stomach wall which led to a correct diagnosis showed a granulomatous infiltrate in the muscularis propria. Characteristic yellow pigment-laden macrophages were seen in the gastric mucosa and pyloric lymph node. Early recognition of this chronic disorder is important not only for proper management but genetic counseling as well.</abstract><cop>United States</cop><pmid>7180966</pmid><doi>10.1097/00000478-198210000-00009</doi><tpages>4</tpages></addata></record> |
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| identifier | ISSN: 0147-5185 |
| ispartof | The American journal of surgical pathology, 1982-10, Vol.6 (7), p.673-676 |
| issn | 0147-5185 |
| language | eng |
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| source | MEDLINE; Journals@Ovid Complete |
| subjects | Granulomatous Disease, Chronic - complications Granulomatous Disease, Chronic - diagnosis Granulomatous Disease, Chronic - pathology Humans Infant Lymph Nodes - pathology Male Pyloric Stenosis - etiology Stomach - pathology Stomach Diseases - complications Stomach Diseases - pathology |
| title | Chronic granulomatous disease of childhood presenting as gastric outlet obstruction |
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