The effect of solvent viscosity on the rate-determining step of fatty acid synthetase

The overall activity of animal fatty acid synthetase at the saturation level of substrate concentration decreased when the solvent viscosity, η, of the reaction mixture was increased with viscogens such as glycerol, sucrose, and polyethylene glycol. The activity of the enzyme changed roughly proport...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Proteins, structure, function, and bioinformatics structure, function, and bioinformatics, 1990, Vol.8 (3), p.287-293
Hauptverfasser:	Kyushiki, Hiroyuki, Ikai, Atsushi
Format:	Artikel
Sprache:	eng
Schlagworte:	analysis Analytical, structural and metabolic biochemistry Biological and medical sciences diffusion limited intramolecular motion effects on Enzymes and enzyme inhibitors Fatty Acid Synthases - chemistry Fatty Acid Synthases - metabolism fatty acid synthetase fatty-acid synthase Fundamental and applied biological sciences. Psychology Kinetics Ligases microviscosity Molecular Weight overall activity rate-determining step solvents Sucrose - chemistry Sucrose - metabolism Temperature Thiolester Hydrolases - chemistry Thiolester Hydrolases - metabolism viscogens Viscosity Water - chemistry
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!