Oestrogen receptor (ER) analysis in B-cell chronic lymphocytic leukemia: Correlation of biochemical and immunocytochemical methods

Oestrogen receptors (ER) are present in neoplastic lymphoid cells and have been considered a physiological marker of growth rate or differentiation. Tamoxifen, an oestrogen antagonist, has been given in some patients with CLL and Hodgkin's disease, with dramatic response in single cases. Until...

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Veröffentlicht in:	Leukemia research 1990, Vol.14 (11), p.949-952
Hauptverfasser:	Melo, N., Hobday, C., Dowsett, M., Catovsky, D., Matutes, E., Morilla, R., Polliack, A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Biological and medical sciences Centrifugation Estradiol - metabolism Female Hematologic and hematopoietic diseases Humans Immunoenzyme Techniques Immunohistochemistry Leukemia, Lymphocytic, Chronic, B-Cell - metabolism Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis Lymphocytes - chemistry Lymphocytes - metabolism Male Medical sciences Middle Aged Receptors, Estrogen - analysis Receptors, Estrogen - metabolism
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