A longitudinal study of platelet behaviour and thromboxane production in whole blood in normal pregnancy and the puerperium
A longitudinal study of platelet behaviour (platelet aggregation and release reaction) in whole blood and of serum thromboxane B2 production was performed before, during and after normal pregnancy. The response of platelets to arachidonic acid and to adrenaline was significantly increased in the thi...
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| Veröffentlicht in: | BJOG : an international journal of obstetrics and gynaecology 1990-12, Vol.97 (12), p.1108-1114 |
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| container_issue | 12 |
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| container_title | BJOG : an international journal of obstetrics and gynaecology |
| container_volume | 97 |
| creator | LOUDEN, K. A. PIPKIN, F. BROUGHTON HEPTINSTALL, S. FOX, S. C. MITCHELL, J. R. A. SYMONDS, E. M. |
| description | A longitudinal study of platelet behaviour (platelet aggregation and release reaction) in whole blood and of serum thromboxane B2 production was performed before, during and after normal pregnancy. The response of platelets to arachidonic acid and to adrenaline was significantly increased in the third trimester. Six weeks after delivery, values were still modestly increased but return to non‐pregnant values was complete by 12 weeks. Serum thromboxane B2 production was unchanged throughout pregnancy and the puerperium. |
| doi_str_mv | 10.1111/j.1471-0528.1990.tb02498.x |
| format | Article |
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M.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A longitudinal study of platelet behaviour and thromboxane production in whole blood in normal pregnancy and the puerperium</atitle><jtitle>BJOG : an international journal of obstetrics and gynaecology</jtitle><addtitle>Br J Obstet Gynaecol</addtitle><date>1990-12</date><risdate>1990</risdate><volume>97</volume><issue>12</issue><spage>1108</spage><epage>1114</epage><pages>1108-1114</pages><issn>1470-0328</issn><issn>0306-5456</issn><eissn>1471-0528</eissn><abstract>A longitudinal study of platelet behaviour (platelet aggregation and release reaction) in whole blood and of serum thromboxane B2 production was performed before, during and after normal pregnancy. The response of platelets to arachidonic acid and to adrenaline was significantly increased in the third trimester. Six weeks after delivery, values were still modestly increased but return to non‐pregnant values was complete by 12 weeks. Serum thromboxane B2 production was unchanged throughout pregnancy and the puerperium.</abstract><cop>Oxford, UK</cop><pub>Blackwell Publishing Ltd</pub><pmid>2126199</pmid><doi>10.1111/j.1471-0528.1990.tb02498.x</doi><tpages>7</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1470-0328 |
| ispartof | BJOG : an international journal of obstetrics and gynaecology, 1990-12, Vol.97 (12), p.1108-1114 |
| issn | 1470-0328 0306-5456 1471-0528 |
| language | eng |
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| source | MEDLINE; Wiley Online Library; Alma/SFX Local Collection |
| subjects | Arachidonic Acid Arachidonic Acids - pharmacology Blood Platelets - drug effects Blood Platelets - physiology Epinephrine - pharmacology Female Humans Longitudinal Studies Platelet Aggregation - physiology Postpartum Period - blood Pregnancy - blood Pregnancy - metabolism Thromboxane B2 - biosynthesis Thromboxane B2 - blood |
| title | A longitudinal study of platelet behaviour and thromboxane production in whole blood in normal pregnancy and the puerperium |
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