The granulocyte-angiotensin system. Angiotensin I-converting activity of cathepsin G

Cathepsin G, an Mr = 26,000-29,000 cationic human neutrophil lysosomal serine protease, releases angiotensin II from angiotensinogen and was, therefore, examined for angiotensin I-converting activity. Cathepsin G-dependent angiotensin I conversion was detected by a high performance liquid chromatogr...

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Veröffentlicht in:	The Journal of biological chemistry 1982-12, Vol.257 (24), p.15042-15046
Hauptverfasser:	Klickstein, L B, Kaempfer, C E, Wintroub, B U
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiotensin I Cathepsin G Cathepsins - blood Chemotactic Factors - pharmacology Humans Kinetics Lysosomes - enzymology N-Formylmethionine - analogs & derivatives N-Formylmethionine - pharmacology N-Formylmethionine Leucyl-Phenylalanine Neutrophils - enzymology Oligopeptides - pharmacology Peptidyl-Dipeptidase A Serine Endopeptidases
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