Localization of the von Hippel-Lindau disease gene to a small region of chromosome 3

We studied 25 families with von Hippel-Lindau disease (VHL) to locate VHL more precisely on chromosome 3. We found that VHL was linked to RAF1, confirming previous observations, and to two polymorphic DNA markers, D3S18 and D3S191. Multipoint linkage analysis indicated that the most likely location...

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Veröffentlicht in:	Genomics (San Diego, Calif.) Calif.), 1990, Vol.8 (4), p.634-640
Hauptverfasser:	Hosoe, Shigeto, Brauch, Hiltrud, Latif, Farida, Glenn, Gladys, Daniel, Gambert, Bale, Sherri, Choyke, Peter, Gorin, Michael, Oldfield, Edward, Berman, Arlene, Goodman, Jack, Orcutt, Mary Lou, Hampsch, Krista, Dllisio, John, Modi, William, McBride, Wesley, Anglard, Patrick, Weiss, Gary, Walther, McClellan M., Linehan, W.Marston, Lerman, Michael I., Zbar, Berton
Format:	Artikel
Sprache:	eng
Schlagworte:	chromosome 3 Chromosome Mapping Chromosomes, Human, Pair 3 Female genes Genes, Dominant Genetic Linkage Humans Male Pedigree Polymorphism, Genetic von Hippel-Lindau Disease - genetics
Online-Zugang:	Volltext
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