Activation and inactivation kinetics of Torpedo californica acetylcholine receptor in reconstituted membranes

By use of a quench-flow technique to measure tracer ion flux rates in a physiologically significant time domain, the kinetics of activation and inactivation of purified reconstituted acetylcholine receptor (AChR) were investigated. After solubilization in sodium cholate, purification by affinity chr...

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Veröffentlicht in:	Biochemistry (Easton) 1982-10, Vol.21 (22), p.5384-5389
Hauptverfasser:	Walker, Jeffrey W, Takeyasu, Kunio, McNamee, Mark G
Format:	Artikel
Sprache:	eng
Schlagworte:	acetylcholine Acetylcholine - metabolism Animals Carbachol - metabolism cations Cations - metabolism chemical kinetics Dose-Response Relationship, Drug Glycine max In Vitro Techniques Ion Channels - metabolism Kinetics Liposomes - metabolism Marine neurotransmitters receptors Receptors, Cholinergic - metabolism reconstitution Rubidium - metabolism Torpedo Torpedo californica
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