PMN-derived proteases enhance the affinity of Fcγ receptor II on myeloid cells, but not on B cells

Treatment of monocytes or K562 cells with proteolytic enzymes like pronase or trypsin, increases both the affinity of the type II Fc receptor for IgG and the signaling via this receptor. In the present study we evaluated whether other proteases could similarly enhance Fcγ RII affinity. We furthermor...

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