Initial and Long-term Results in the Management of Primary Chest Wall Neoplasms

One hundred ten patients with primary chest wall neoplasms were analyzed for long-term results. The diagnosis of 59 malignant and 51 benign tumors was confirmed by the Armed Forces Institute of Pathology. No deaths were associated with primary definitive therapy. Among the five most frequently encou...

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Veröffentlicht in:The Annals of thoracic surgery 1982-12, Vol.34 (6), p.664-673
Hauptverfasser: Graeber, Geoffrey M., Snyder, Robert J., Fleming, Arthur W., Head, Harold D., Lough, Frederick C., Parker, John S., Zajtchuk, Rostik, Brott, Walter H.
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container_end_page 673
container_issue 6
container_start_page 664
container_title The Annals of thoracic surgery
container_volume 34
creator Graeber, Geoffrey M.
Snyder, Robert J.
Fleming, Arthur W.
Head, Harold D.
Lough, Frederick C.
Parker, John S.
Zajtchuk, Rostik
Brott, Walter H.
description One hundred ten patients with primary chest wall neoplasms were analyzed for long-term results. The diagnosis of 59 malignant and 51 benign tumors was confirmed by the Armed Forces Institute of Pathology. No deaths were associated with primary definitive therapy. Among the five most frequently encountered malignant tumor types, five-year survivals were obtained in 9 of 17 (53%) patients with fibrosarcoma, 8 of 9 (89%) patients with chondrosarcoma, 2 of 8 (25%) patients with solitary chest wall plasmacytoma (multiple myeloma), 1 of 6 (17%) patients with Ewing's sarcoma, and 2 of 4 (50%) of patients with osteogenic sarcoma. Although the five-year survival appears to indicate therapeutic success in patients with Ewing's sarcoma and osteogenic sarcoma, patients with chondrosarcoma or fibrosarcoma may have a more protracted course, and those with solitary plasmacytoma usually develop multiple myeloma. The findings suggest that radical surgical excision is the treatment of choice for chondrosarcoma; radical surgical excision combined with chemotherapy, for fibrosarcoma and osteogenic sarcoma; surgical excision combined with radiation and chemotherapy, for Ewing's sarcoma; and systemic surveillance and therapy, for pathologically confirmed solitary plasmacytoma.
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source MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Alma/SFX Local Collection
subjects Adolescent
Adult
Aged
Child
Chondrosarcoma - therapy
Female
Fibrosarcoma - therapy
Humans
Male
Middle Aged
Multiple Myeloma - therapy
Osteosarcoma - therapy
Sarcoma, Ewing - therapy
Thoracic Neoplasms - mortality
Thoracic Neoplasms - therapy
title Initial and Long-term Results in the Management of Primary Chest Wall Neoplasms
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