Flumethason-induced calving is preceded by a period of myometrial inhibition during luteolysis

The temporal relationship among changes of the concentrations of the 13,14-dihydro-15-keto metabolite of prostaglandin F2 alpha (PGFM), estrone (E1) and estrone sulphate (E1S) in maternal arterial plasma (MP) and amniotic fluid (AF), the prepartum progesterone (P4) decline in MP, and the evolution o...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Biology of reproduction 1990-09, Vol.43 (3), p.466-471
Hauptverfasser: Janszen, B.P.M. (University of Utrecht, Utrecht, The Netherlands), Knijn, H, Weyden, G.C. van der, Bevers, M.M, Dieleman, S.J, Taverne, M.A.M
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 471
container_issue 3
container_start_page 466
container_title Biology of reproduction
container_volume 43
creator Janszen, B.P.M. (University of Utrecht, Utrecht, The Netherlands)
Knijn, H
Weyden, G.C. van der
Bevers, M.M
Dieleman, S.J
Taverne, M.A.M
description The temporal relationship among changes of the concentrations of the 13,14-dihydro-15-keto metabolite of prostaglandin F2 alpha (PGFM), estrone (E1) and estrone sulphate (E1S) in maternal arterial plasma (MP) and amniotic fluid (AF), the prepartum progesterone (P4) decline in MP, and the evolution of uterine electromyographic (EMG) activity was investigated in 6 cows. Calving was induced by a single i.m. injection of 5 mg flumethason on Day 270 of gestation. The period under investigation was subdivided into four consecutive periods: Period 1 covered the last 2 days before flumethason treatment; Period 2 (mean +/- SEM duration: 16.1 +/- 2.5 h), Period 3 (8.8 +/- 1.1 h), and Period 4 (13.0 +/- 1.5 h) together included the interval between injection and the onset of the expulsive stage of induced parturition. Each was defined by its pattern of uterine EMG activity. During Periods 1 and 2, this activity occurred in long episodes (2-20 min; contractures) at a similar mean (+/- SEM) frequency (0.51 +/- 0.14/h and 0.42 +/- 0.07/h, respectively). No significant differences in hormonal concentrations in MP and AF between these two periods were detected. During Period 3, contractures nearly disappeared (freq: 0.09 +/- 0.05/h), and in MP mean P4 levels were significantly lower and PGFM levels were significantly higher than before. Mean PGFM concentrations in AF were not significantly changed during Period 3. Finally, during Period 4, EMG activity reappeared and a parturient EMG pattern gradually evolved in the presence of a further significant decline of P4 levels and significant increase of PGFM concentrations in MP.
doi_str_mv 10.1095/biolreprod43.3.466
format Article
fullrecord <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_80211082</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>80211082</sourcerecordid><originalsourceid>FETCH-LOGICAL-c377t-93e5211b8be84d31b80c5798016de7cb8c11c3e657b3ff312422e8b087c59b773</originalsourceid><addsrcrecordid>eNpNkMFq3DAQhkVoSTdpXyBQ0KW9eStpbEs-ltA0hUAPTa4RkjzeVZCtrWRn2bevwi5NThIz__8NfIRccbbmrGu-WR9Dwl2KfQ1rWNdte0ZWvBFdJUWr3pEVY6ytAFr4QC5yfmKM1yDgnJwLIbkUckUeb8Iy4rw1OU6Vn_rFYU-dCc9-2lCf6S5hmZSZPVBDd5h87Gkc6HiIpZa8CdRPW2_97ONE-yW99MIyYwyH7PNH8n4wIeOn03tJHm5-3F_fVne_f_66_n5XOZByrjrARnBulUVV91A-zDWyU4y3PUpnlePcAbaNtDAMwEUtBCrLlHRNZ6WES_L1yC0y_i6YZz367DAEM2Fcslas4JkSJSiOQZdizgkHvUt-NOmgOdMvUvVbqRp0kVpKn0_0xY7Y_6-cLJb9l9Pe5OJuSGZyPr-Su7puRAuvua3fbPc-oc6jCaFQQe_3-zf3ro65wURtNqmwHv50nLWKSfgHVBqYsw</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>80211082</pqid></control><display><type>article</type><title>Flumethason-induced calving is preceded by a period of myometrial inhibition during luteolysis</title><source>MEDLINE</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><creator>Janszen, B.P.M. (University of Utrecht, Utrecht, The Netherlands) ; Knijn, H ; Weyden, G.C. van der ; Bevers, M.M ; Dieleman, S.J ; Taverne, M.A.M</creator><creatorcontrib>Janszen, B.P.M. (University of Utrecht, Utrecht, The Netherlands) ; Knijn, H ; Weyden, G.C. van der ; Bevers, M.M ; Dieleman, S.J ; Taverne, M.A.M</creatorcontrib><description>The temporal relationship among changes of the concentrations of the 13,14-dihydro-15-keto metabolite of prostaglandin F2 alpha (PGFM), estrone (E1) and estrone sulphate (E1S) in maternal arterial plasma (MP) and amniotic fluid (AF), the prepartum progesterone (P4) decline in MP, and the evolution of uterine electromyographic (EMG) activity was investigated in 6 cows. Calving was induced by a single i.m. injection of 5 mg flumethason on Day 270 of gestation. The period under investigation was subdivided into four consecutive periods: Period 1 covered the last 2 days before flumethason treatment; Period 2 (mean +/- SEM duration: 16.1 +/- 2.5 h), Period 3 (8.8 +/- 1.1 h), and Period 4 (13.0 +/- 1.5 h) together included the interval between injection and the onset of the expulsive stage of induced parturition. Each was defined by its pattern of uterine EMG activity. During Periods 1 and 2, this activity occurred in long episodes (2-20 min; contractures) at a similar mean (+/- SEM) frequency (0.51 +/- 0.14/h and 0.42 +/- 0.07/h, respectively). No significant differences in hormonal concentrations in MP and AF between these two periods were detected. During Period 3, contractures nearly disappeared (freq: 0.09 +/- 0.05/h), and in MP mean P4 levels were significantly lower and PGFM levels were significantly higher than before. Mean PGFM concentrations in AF were not significantly changed during Period 3. Finally, during Period 4, EMG activity reappeared and a parturient EMG pattern gradually evolved in the presence of a further significant decline of P4 levels and significant increase of PGFM concentrations in MP.</description><identifier>ISSN: 0006-3363</identifier><identifier>EISSN: 1529-7268</identifier><identifier>DOI: 10.1095/biolreprod43.3.466</identifier><identifier>PMID: 2271727</identifier><identifier>CODEN: BIREBV</identifier><language>eng</language><publisher>Madison, WI: Society for the Study of Reproduction</publisher><subject>AMNIOTIC FLUID ; Amniotic Fluid - metabolism ; Animals ; Biological and medical sciences ; BODY FLUIDS ; CARACT MICROMORFOLOGICAS DEL SUELO ; Cattle - physiology ; CICLO ESTRAL ; COWS ; CYCLE OESTRAL ; Dinoprost - analogs &amp; derivatives ; Dinoprost - biosynthesis ; Electromyography ; ESTEROIDES ; ESTROGENOS ; ESTRONE ; Estrone - analogs &amp; derivatives ; Estrone - metabolism ; Female ; FLUMETASONE ; Flumethasone - pharmacology ; Fundamental and applied biological sciences. Psychology ; HORMONAS SINTETICAS ; Hormone metabolism and regulation ; HORMONE SYNTHETIQUE ; Labor, Induced ; LIQUIDE BIOLOGIQUE ; LIQUIDOS CORPORALES ; MYOMETRIUM ; Myometrium - drug effects ; OESTROGENE ; OESTROGENS ; OESTROUS CYCLE ; PARTO ; PARTURITION ; PLASMA ; Pregnancy ; Pregnancy. Parturition. Lactation ; Progesterone - blood ; PROSTAGLANDINAS ; PROSTAGLANDINE ; PROSTAGLANDINS ; SOIL MICROMORPHOLOGICAL FEATURES ; STEROIDE ; STEROIDS ; SYNTHETIC HORMONES ; TRAIT MICROMORPHOLOGIQUE DU SOL ; Uterine Contraction - drug effects ; UTERO ; UTERUS ; VACA ; VACHE ; Vertebrates: reproduction</subject><ispartof>Biology of reproduction, 1990-09, Vol.43 (3), p.466-471</ispartof><rights>1991 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c377t-93e5211b8be84d31b80c5798016de7cb8c11c3e657b3ff312422e8b087c59b773</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&amp;idt=19445263$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/2271727$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Janszen, B.P.M. (University of Utrecht, Utrecht, The Netherlands)</creatorcontrib><creatorcontrib>Knijn, H</creatorcontrib><creatorcontrib>Weyden, G.C. van der</creatorcontrib><creatorcontrib>Bevers, M.M</creatorcontrib><creatorcontrib>Dieleman, S.J</creatorcontrib><creatorcontrib>Taverne, M.A.M</creatorcontrib><title>Flumethason-induced calving is preceded by a period of myometrial inhibition during luteolysis</title><title>Biology of reproduction</title><addtitle>Biol Reprod</addtitle><description>The temporal relationship among changes of the concentrations of the 13,14-dihydro-15-keto metabolite of prostaglandin F2 alpha (PGFM), estrone (E1) and estrone sulphate (E1S) in maternal arterial plasma (MP) and amniotic fluid (AF), the prepartum progesterone (P4) decline in MP, and the evolution of uterine electromyographic (EMG) activity was investigated in 6 cows. Calving was induced by a single i.m. injection of 5 mg flumethason on Day 270 of gestation. The period under investigation was subdivided into four consecutive periods: Period 1 covered the last 2 days before flumethason treatment; Period 2 (mean +/- SEM duration: 16.1 +/- 2.5 h), Period 3 (8.8 +/- 1.1 h), and Period 4 (13.0 +/- 1.5 h) together included the interval between injection and the onset of the expulsive stage of induced parturition. Each was defined by its pattern of uterine EMG activity. During Periods 1 and 2, this activity occurred in long episodes (2-20 min; contractures) at a similar mean (+/- SEM) frequency (0.51 +/- 0.14/h and 0.42 +/- 0.07/h, respectively). No significant differences in hormonal concentrations in MP and AF between these two periods were detected. During Period 3, contractures nearly disappeared (freq: 0.09 +/- 0.05/h), and in MP mean P4 levels were significantly lower and PGFM levels were significantly higher than before. Mean PGFM concentrations in AF were not significantly changed during Period 3. Finally, during Period 4, EMG activity reappeared and a parturient EMG pattern gradually evolved in the presence of a further significant decline of P4 levels and significant increase of PGFM concentrations in MP.</description><subject>AMNIOTIC FLUID</subject><subject>Amniotic Fluid - metabolism</subject><subject>Animals</subject><subject>Biological and medical sciences</subject><subject>BODY FLUIDS</subject><subject>CARACT MICROMORFOLOGICAS DEL SUELO</subject><subject>Cattle - physiology</subject><subject>CICLO ESTRAL</subject><subject>COWS</subject><subject>CYCLE OESTRAL</subject><subject>Dinoprost - analogs &amp; derivatives</subject><subject>Dinoprost - biosynthesis</subject><subject>Electromyography</subject><subject>ESTEROIDES</subject><subject>ESTROGENOS</subject><subject>ESTRONE</subject><subject>Estrone - analogs &amp; derivatives</subject><subject>Estrone - metabolism</subject><subject>Female</subject><subject>FLUMETASONE</subject><subject>Flumethasone - pharmacology</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>HORMONAS SINTETICAS</subject><subject>Hormone metabolism and regulation</subject><subject>HORMONE SYNTHETIQUE</subject><subject>Labor, Induced</subject><subject>LIQUIDE BIOLOGIQUE</subject><subject>LIQUIDOS CORPORALES</subject><subject>MYOMETRIUM</subject><subject>Myometrium - drug effects</subject><subject>OESTROGENE</subject><subject>OESTROGENS</subject><subject>OESTROUS CYCLE</subject><subject>PARTO</subject><subject>PARTURITION</subject><subject>PLASMA</subject><subject>Pregnancy</subject><subject>Pregnancy. Parturition. Lactation</subject><subject>Progesterone - blood</subject><subject>PROSTAGLANDINAS</subject><subject>PROSTAGLANDINE</subject><subject>PROSTAGLANDINS</subject><subject>SOIL MICROMORPHOLOGICAL FEATURES</subject><subject>STEROIDE</subject><subject>STEROIDS</subject><subject>SYNTHETIC HORMONES</subject><subject>TRAIT MICROMORPHOLOGIQUE DU SOL</subject><subject>Uterine Contraction - drug effects</subject><subject>UTERO</subject><subject>UTERUS</subject><subject>VACA</subject><subject>VACHE</subject><subject>Vertebrates: reproduction</subject><issn>0006-3363</issn><issn>1529-7268</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1990</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpNkMFq3DAQhkVoSTdpXyBQ0KW9eStpbEs-ltA0hUAPTa4RkjzeVZCtrWRn2bevwi5NThIz__8NfIRccbbmrGu-WR9Dwl2KfQ1rWNdte0ZWvBFdJUWr3pEVY6ytAFr4QC5yfmKM1yDgnJwLIbkUckUeb8Iy4rw1OU6Vn_rFYU-dCc9-2lCf6S5hmZSZPVBDd5h87Gkc6HiIpZa8CdRPW2_97ONE-yW99MIyYwyH7PNH8n4wIeOn03tJHm5-3F_fVne_f_66_n5XOZByrjrARnBulUVV91A-zDWyU4y3PUpnlePcAbaNtDAMwEUtBCrLlHRNZ6WES_L1yC0y_i6YZz367DAEM2Fcslas4JkSJSiOQZdizgkHvUt-NOmgOdMvUvVbqRp0kVpKn0_0xY7Y_6-cLJb9l9Pe5OJuSGZyPr-Su7puRAuvua3fbPc-oc6jCaFQQe_3-zf3ro65wURtNqmwHv50nLWKSfgHVBqYsw</recordid><startdate>19900901</startdate><enddate>19900901</enddate><creator>Janszen, B.P.M. (University of Utrecht, Utrecht, The Netherlands)</creator><creator>Knijn, H</creator><creator>Weyden, G.C. van der</creator><creator>Bevers, M.M</creator><creator>Dieleman, S.J</creator><creator>Taverne, M.A.M</creator><general>Society for the Study of Reproduction</general><scope>FBQ</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19900901</creationdate><title>Flumethason-induced calving is preceded by a period of myometrial inhibition during luteolysis</title><author>Janszen, B.P.M. (University of Utrecht, Utrecht, The Netherlands) ; Knijn, H ; Weyden, G.C. van der ; Bevers, M.M ; Dieleman, S.J ; Taverne, M.A.M</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c377t-93e5211b8be84d31b80c5798016de7cb8c11c3e657b3ff312422e8b087c59b773</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1990</creationdate><topic>AMNIOTIC FLUID</topic><topic>Amniotic Fluid - metabolism</topic><topic>Animals</topic><topic>Biological and medical sciences</topic><topic>BODY FLUIDS</topic><topic>CARACT MICROMORFOLOGICAS DEL SUELO</topic><topic>Cattle - physiology</topic><topic>CICLO ESTRAL</topic><topic>COWS</topic><topic>CYCLE OESTRAL</topic><topic>Dinoprost - analogs &amp; derivatives</topic><topic>Dinoprost - biosynthesis</topic><topic>Electromyography</topic><topic>ESTEROIDES</topic><topic>ESTROGENOS</topic><topic>ESTRONE</topic><topic>Estrone - analogs &amp; derivatives</topic><topic>Estrone - metabolism</topic><topic>Female</topic><topic>FLUMETASONE</topic><topic>Flumethasone - pharmacology</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>HORMONAS SINTETICAS</topic><topic>Hormone metabolism and regulation</topic><topic>HORMONE SYNTHETIQUE</topic><topic>Labor, Induced</topic><topic>LIQUIDE BIOLOGIQUE</topic><topic>LIQUIDOS CORPORALES</topic><topic>MYOMETRIUM</topic><topic>Myometrium - drug effects</topic><topic>OESTROGENE</topic><topic>OESTROGENS</topic><topic>OESTROUS CYCLE</topic><topic>PARTO</topic><topic>PARTURITION</topic><topic>PLASMA</topic><topic>Pregnancy</topic><topic>Pregnancy. Parturition. Lactation</topic><topic>Progesterone - blood</topic><topic>PROSTAGLANDINAS</topic><topic>PROSTAGLANDINE</topic><topic>PROSTAGLANDINS</topic><topic>SOIL MICROMORPHOLOGICAL FEATURES</topic><topic>STEROIDE</topic><topic>STEROIDS</topic><topic>SYNTHETIC HORMONES</topic><topic>TRAIT MICROMORPHOLOGIQUE DU SOL</topic><topic>Uterine Contraction - drug effects</topic><topic>UTERO</topic><topic>UTERUS</topic><topic>VACA</topic><topic>VACHE</topic><topic>Vertebrates: reproduction</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Janszen, B.P.M. (University of Utrecht, Utrecht, The Netherlands)</creatorcontrib><creatorcontrib>Knijn, H</creatorcontrib><creatorcontrib>Weyden, G.C. van der</creatorcontrib><creatorcontrib>Bevers, M.M</creatorcontrib><creatorcontrib>Dieleman, S.J</creatorcontrib><creatorcontrib>Taverne, M.A.M</creatorcontrib><collection>AGRIS</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Biology of reproduction</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Janszen, B.P.M. (University of Utrecht, Utrecht, The Netherlands)</au><au>Knijn, H</au><au>Weyden, G.C. van der</au><au>Bevers, M.M</au><au>Dieleman, S.J</au><au>Taverne, M.A.M</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Flumethason-induced calving is preceded by a period of myometrial inhibition during luteolysis</atitle><jtitle>Biology of reproduction</jtitle><addtitle>Biol Reprod</addtitle><date>1990-09-01</date><risdate>1990</risdate><volume>43</volume><issue>3</issue><spage>466</spage><epage>471</epage><pages>466-471</pages><issn>0006-3363</issn><eissn>1529-7268</eissn><coden>BIREBV</coden><abstract>The temporal relationship among changes of the concentrations of the 13,14-dihydro-15-keto metabolite of prostaglandin F2 alpha (PGFM), estrone (E1) and estrone sulphate (E1S) in maternal arterial plasma (MP) and amniotic fluid (AF), the prepartum progesterone (P4) decline in MP, and the evolution of uterine electromyographic (EMG) activity was investigated in 6 cows. Calving was induced by a single i.m. injection of 5 mg flumethason on Day 270 of gestation. The period under investigation was subdivided into four consecutive periods: Period 1 covered the last 2 days before flumethason treatment; Period 2 (mean +/- SEM duration: 16.1 +/- 2.5 h), Period 3 (8.8 +/- 1.1 h), and Period 4 (13.0 +/- 1.5 h) together included the interval between injection and the onset of the expulsive stage of induced parturition. Each was defined by its pattern of uterine EMG activity. During Periods 1 and 2, this activity occurred in long episodes (2-20 min; contractures) at a similar mean (+/- SEM) frequency (0.51 +/- 0.14/h and 0.42 +/- 0.07/h, respectively). No significant differences in hormonal concentrations in MP and AF between these two periods were detected. During Period 3, contractures nearly disappeared (freq: 0.09 +/- 0.05/h), and in MP mean P4 levels were significantly lower and PGFM levels were significantly higher than before. Mean PGFM concentrations in AF were not significantly changed during Period 3. Finally, during Period 4, EMG activity reappeared and a parturient EMG pattern gradually evolved in the presence of a further significant decline of P4 levels and significant increase of PGFM concentrations in MP.</abstract><cop>Madison, WI</cop><pub>Society for the Study of Reproduction</pub><pmid>2271727</pmid><doi>10.1095/biolreprod43.3.466</doi><tpages>6</tpages></addata></record>
fulltext fulltext
identifier ISSN: 0006-3363
ispartof Biology of reproduction, 1990-09, Vol.43 (3), p.466-471
issn 0006-3363
1529-7268
language eng
recordid cdi_proquest_miscellaneous_80211082
source MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals
subjects AMNIOTIC FLUID
Amniotic Fluid - metabolism
Animals
Biological and medical sciences
BODY FLUIDS
CARACT MICROMORFOLOGICAS DEL SUELO
Cattle - physiology
CICLO ESTRAL
COWS
CYCLE OESTRAL
Dinoprost - analogs & derivatives
Dinoprost - biosynthesis
Electromyography
ESTEROIDES
ESTROGENOS
ESTRONE
Estrone - analogs & derivatives
Estrone - metabolism
Female
FLUMETASONE
Flumethasone - pharmacology
Fundamental and applied biological sciences. Psychology
HORMONAS SINTETICAS
Hormone metabolism and regulation
HORMONE SYNTHETIQUE
Labor, Induced
LIQUIDE BIOLOGIQUE
LIQUIDOS CORPORALES
MYOMETRIUM
Myometrium - drug effects
OESTROGENE
OESTROGENS
OESTROUS CYCLE
PARTO
PARTURITION
PLASMA
Pregnancy
Pregnancy. Parturition. Lactation
Progesterone - blood
PROSTAGLANDINAS
PROSTAGLANDINE
PROSTAGLANDINS
SOIL MICROMORPHOLOGICAL FEATURES
STEROIDE
STEROIDS
SYNTHETIC HORMONES
TRAIT MICROMORPHOLOGIQUE DU SOL
Uterine Contraction - drug effects
UTERO
UTERUS
VACA
VACHE
Vertebrates: reproduction
title Flumethason-induced calving is preceded by a period of myometrial inhibition during luteolysis
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-09T13%3A54%3A55IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Flumethason-induced%20calving%20is%20preceded%20by%20a%20period%20of%20myometrial%20inhibition%20during%20luteolysis&rft.jtitle=Biology%20of%20reproduction&rft.au=Janszen,%20B.P.M.%20(University%20of%20Utrecht,%20Utrecht,%20The%20Netherlands)&rft.date=1990-09-01&rft.volume=43&rft.issue=3&rft.spage=466&rft.epage=471&rft.pages=466-471&rft.issn=0006-3363&rft.eissn=1529-7268&rft.coden=BIREBV&rft_id=info:doi/10.1095/biolreprod43.3.466&rft_dat=%3Cproquest_cross%3E80211082%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=80211082&rft_id=info:pmid/2271727&rfr_iscdi=true