Cholecystokinin cholecystography, sonography, and scintigraphy: detection of chronic acalculous cholecystitis
Because the efficacy of cholecystokinin cholecystography in the detection of chronic acalculous cholecystitis remains in doubt, the procedure is rarely used in clinical practice. However, the ability to observe gallbladder contraction with sonography and 99mTc-para-isopropylacetanilido-iminodiacetic...
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Veröffentlicht in: | AJR, Am. J. Roentgenol.; (United States) Am. J. Roentgenol.; (United States), 1982-12, Vol.139 (6), p.1117-1121 |
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description | Because the efficacy of cholecystokinin cholecystography in the detection of chronic acalculous cholecystitis remains in doubt, the procedure is rarely used in clinical practice. However, the ability to observe gallbladder contraction with sonography and 99mTc-para-isopropylacetanilido-iminodiacetic acid cholescintigraphy (PIPIDA) offers a possibility to improve the sensitivity of the test. To determine if the degree of gallbladder contraction after cholecystokinin is the same as measured by the three techniques and if it differs in symptomatic patients compared to the normal population, cholecystokinin cholecystography, cholecystokinin sonography, and cholecystokinin PIPIDA were performed in 10 symptomatic patients and 10 normal volunteers. The mean maximum contraction of the gallbladder during the three studies was 63%, 61%, and 68%, respectively, for the volunteers, and 72%, 63%, and 73%, respectively, for the patients. The mean maximum gallbladder contraction during all three procedures was 64% +/- 26% SD in the volunteers and 74% +/- 17% SD in the patients. The differences were not statistically significant. Although there was good correlation in the degree of maximum gallbladder contraction among cholecystokinin cholecystography, cholecystokinin sonography, and cholecystokinin PIPIDA, marked variation in both the volunteers and the patients makes it unlikely that the degree of contraction as observed by any of these techniques can be used to indicate the presence of chronic acalculous cholecystitis. |
doi_str_mv | 10.2214/ajr.139.6.1117 |
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However, the ability to observe gallbladder contraction with sonography and 99mTc-para-isopropylacetanilido-iminodiacetic acid cholescintigraphy (PIPIDA) offers a possibility to improve the sensitivity of the test. To determine if the degree of gallbladder contraction after cholecystokinin is the same as measured by the three techniques and if it differs in symptomatic patients compared to the normal population, cholecystokinin cholecystography, cholecystokinin sonography, and cholecystokinin PIPIDA were performed in 10 symptomatic patients and 10 normal volunteers. The mean maximum contraction of the gallbladder during the three studies was 63%, 61%, and 68%, respectively, for the volunteers, and 72%, 63%, and 73%, respectively, for the patients. The mean maximum gallbladder contraction during all three procedures was 64% +/- 26% SD in the volunteers and 74% +/- 17% SD in the patients. The differences were not statistically significant. Although there was good correlation in the degree of maximum gallbladder contraction among cholecystokinin cholecystography, cholecystokinin sonography, and cholecystokinin PIPIDA, marked variation in both the volunteers and the patients makes it unlikely that the degree of contraction as observed by any of these techniques can be used to indicate the presence of chronic acalculous cholecystitis.</description><identifier>ISSN: 0361-803X</identifier><identifier>EISSN: 1546-3141</identifier><identifier>DOI: 10.2214/ajr.139.6.1117</identifier><identifier>PMID: 6983255</identifier><language>eng</language><publisher>United States: Am Roentgen Ray Soc</publisher><subject>550601 - Medicine- Unsealed Radionuclides in Diagnostics ; 550602 - Medicine- External Radiation in Diagnostics- (1980-) ; AMINO ACIDS ; BETA DECAY RADIOISOTOPES ; BETA-MINUS DECAY RADIOISOTOPES ; Biliary Dyskinesia - diagnosis ; BILIARY TRACT ; CARBOXYLIC ACIDS ; CHELATING AGENTS ; Cholecystectomy ; Cholecystitis - diagnosis ; Cholecystitis - pathology ; Cholecystitis - surgery ; Cholecystography ; Cholecystokinin - pharmacology ; CONTRACTION ; COUNTING TECHNIQUES ; DIAGNOSIS ; DIAGNOSTIC TECHNIQUES ; DIGESTIVE SYSTEM ; DIGESTIVE SYSTEM DISEASES ; DISEASES ; Follow-Up Studies ; Gallbladder - diagnostic imaging ; Gallbladder - drug effects ; HOURS LIVING RADIOISOTOPES ; Humans ; Imino Acids ; INTERMEDIATE MASS NUCLEI ; ISOMERIC NUCLEI ; ISOMERIC TRANSITION ISOTOPES ; ISOTOPES ; Muscle Contraction - drug effects ; NUCLEI ; ODD-EVEN NUCLEI ; ORGANIC ACIDS ; ORGANIC COMPOUNDS ; Organotechnetium Compounds ; PATIENTS ; RADIOISOTOPE SCANNING ; RADIOISOTOPES ; RADIOLOGY AND NUCLEAR MEDICINE ; Radionuclide Imaging ; SCINTISCANNING ; Technetium ; TECHNETIUM 99 ; TECHNETIUM ISOTOPES ; ULTRASONOGRAPHY ; YEARS LIVING RADIOISOTOPES</subject><ispartof>AJR, Am. 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Roentgenol.; (United States), 1982-12, Vol.139 (6), p.1117-1121</ispartof><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c389t-4be548942ff93f7fd9c4aa5b8956656b50fccbc50b2c263482046a76ecd0461f3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,881,4106,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/6983255$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink><backlink>$$Uhttps://www.osti.gov/biblio/6172948$$D View this record in Osti.gov$$Hfree_for_read</backlink></links><search><creatorcontrib>Davis, GB</creatorcontrib><creatorcontrib>Berk, RN</creatorcontrib><creatorcontrib>Scheible, FW</creatorcontrib><creatorcontrib>Witztum, KF</creatorcontrib><creatorcontrib>Gilmore, IT</creatorcontrib><creatorcontrib>Strong, RM</creatorcontrib><creatorcontrib>Hofmann, AF</creatorcontrib><title>Cholecystokinin cholecystography, sonography, and scintigraphy: detection of chronic acalculous cholecystitis</title><title>AJR, Am. J. Roentgenol.; (United States)</title><addtitle>AJR Am J Roentgenol</addtitle><description>Because the efficacy of cholecystokinin cholecystography in the detection of chronic acalculous cholecystitis remains in doubt, the procedure is rarely used in clinical practice. However, the ability to observe gallbladder contraction with sonography and 99mTc-para-isopropylacetanilido-iminodiacetic acid cholescintigraphy (PIPIDA) offers a possibility to improve the sensitivity of the test. To determine if the degree of gallbladder contraction after cholecystokinin is the same as measured by the three techniques and if it differs in symptomatic patients compared to the normal population, cholecystokinin cholecystography, cholecystokinin sonography, and cholecystokinin PIPIDA were performed in 10 symptomatic patients and 10 normal volunteers. The mean maximum contraction of the gallbladder during the three studies was 63%, 61%, and 68%, respectively, for the volunteers, and 72%, 63%, and 73%, respectively, for the patients. The mean maximum gallbladder contraction during all three procedures was 64% +/- 26% SD in the volunteers and 74% +/- 17% SD in the patients. The differences were not statistically significant. Although there was good correlation in the degree of maximum gallbladder contraction among cholecystokinin cholecystography, cholecystokinin sonography, and cholecystokinin PIPIDA, marked variation in both the volunteers and the patients makes it unlikely that the degree of contraction as observed by any of these techniques can be used to indicate the presence of chronic acalculous cholecystitis.</description><subject>550601 - Medicine- Unsealed Radionuclides in Diagnostics</subject><subject>550602 - Medicine- External Radiation in Diagnostics- (1980-)</subject><subject>AMINO ACIDS</subject><subject>BETA DECAY RADIOISOTOPES</subject><subject>BETA-MINUS DECAY RADIOISOTOPES</subject><subject>Biliary Dyskinesia - diagnosis</subject><subject>BILIARY TRACT</subject><subject>CARBOXYLIC ACIDS</subject><subject>CHELATING AGENTS</subject><subject>Cholecystectomy</subject><subject>Cholecystitis - diagnosis</subject><subject>Cholecystitis - pathology</subject><subject>Cholecystitis - surgery</subject><subject>Cholecystography</subject><subject>Cholecystokinin - pharmacology</subject><subject>CONTRACTION</subject><subject>COUNTING TECHNIQUES</subject><subject>DIAGNOSIS</subject><subject>DIAGNOSTIC TECHNIQUES</subject><subject>DIGESTIVE SYSTEM</subject><subject>DIGESTIVE SYSTEM DISEASES</subject><subject>DISEASES</subject><subject>Follow-Up Studies</subject><subject>Gallbladder - diagnostic imaging</subject><subject>Gallbladder - drug effects</subject><subject>HOURS LIVING RADIOISOTOPES</subject><subject>Humans</subject><subject>Imino Acids</subject><subject>INTERMEDIATE MASS NUCLEI</subject><subject>ISOMERIC NUCLEI</subject><subject>ISOMERIC TRANSITION ISOTOPES</subject><subject>ISOTOPES</subject><subject>Muscle Contraction - drug effects</subject><subject>NUCLEI</subject><subject>ODD-EVEN NUCLEI</subject><subject>ORGANIC ACIDS</subject><subject>ORGANIC COMPOUNDS</subject><subject>Organotechnetium Compounds</subject><subject>PATIENTS</subject><subject>RADIOISOTOPE SCANNING</subject><subject>RADIOISOTOPES</subject><subject>RADIOLOGY AND NUCLEAR MEDICINE</subject><subject>Radionuclide Imaging</subject><subject>SCINTISCANNING</subject><subject>Technetium</subject><subject>TECHNETIUM 99</subject><subject>TECHNETIUM ISOTOPES</subject><subject>ULTRASONOGRAPHY</subject><subject>YEARS LIVING RADIOISOTOPES</subject><issn>0361-803X</issn><issn>1546-3141</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1982</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpNkUtr3DAUhUVpSSZpt90VTBfJJnb1ttRdGfIoBLppoTshy1KsxJYmkodh_n0UPEyy0pXud8896ADwFcEGY0R_6MfUICIb3iCE2g9ghRjlNUEUfQQrSDiqBST_T8FZzo8QwlbI9gSccCkIZmwFpvUQR2v2eY5PPvhQmeP9IenNsL-qcgzHWoe-ysaH2S8vP6veztbMPoYqujKcYvCm0kaPZjvGbX7T87PPn8Enp8dsvxzOc_Dv5vrv-q6-_3P7e_3rvjZEyLmmnWVUSIqdk8S1rpeGas06IRnnjHcMOmM6w2CHDeaECgwp1y23pi8FcuQcfF90Y9mriuHicTAxhGJVcdRiSUWBLhZok-Lz1uZZTT4bO4462OJcCYhhKzkpYLOAJsWck3Vqk_yk014hqF5DUCUEVUJQXL2GUAa-HZS33WT7I3749dK_XPqDfxh2PlmVJz2OhUZqt9u9U3oBGsCS5g</recordid><startdate>198212</startdate><enddate>198212</enddate><creator>Davis, GB</creator><creator>Berk, RN</creator><creator>Scheible, FW</creator><creator>Witztum, KF</creator><creator>Gilmore, IT</creator><creator>Strong, RM</creator><creator>Hofmann, AF</creator><general>Am Roentgen Ray Soc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>OTOTI</scope></search><sort><creationdate>198212</creationdate><title>Cholecystokinin cholecystography, sonography, and scintigraphy: detection of chronic acalculous cholecystitis</title><author>Davis, GB ; Berk, RN ; Scheible, FW ; Witztum, KF ; Gilmore, IT ; Strong, RM ; Hofmann, AF</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c389t-4be548942ff93f7fd9c4aa5b8956656b50fccbc50b2c263482046a76ecd0461f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1982</creationdate><topic>550601 - Medicine- Unsealed Radionuclides in Diagnostics</topic><topic>550602 - Medicine- External Radiation in Diagnostics- (1980-)</topic><topic>AMINO ACIDS</topic><topic>BETA DECAY RADIOISOTOPES</topic><topic>BETA-MINUS DECAY RADIOISOTOPES</topic><topic>Biliary Dyskinesia - diagnosis</topic><topic>BILIARY TRACT</topic><topic>CARBOXYLIC ACIDS</topic><topic>CHELATING AGENTS</topic><topic>Cholecystectomy</topic><topic>Cholecystitis - diagnosis</topic><topic>Cholecystitis - pathology</topic><topic>Cholecystitis - surgery</topic><topic>Cholecystography</topic><topic>Cholecystokinin - pharmacology</topic><topic>CONTRACTION</topic><topic>COUNTING TECHNIQUES</topic><topic>DIAGNOSIS</topic><topic>DIAGNOSTIC TECHNIQUES</topic><topic>DIGESTIVE SYSTEM</topic><topic>DIGESTIVE SYSTEM DISEASES</topic><topic>DISEASES</topic><topic>Follow-Up Studies</topic><topic>Gallbladder - diagnostic imaging</topic><topic>Gallbladder - drug effects</topic><topic>HOURS LIVING RADIOISOTOPES</topic><topic>Humans</topic><topic>Imino Acids</topic><topic>INTERMEDIATE MASS NUCLEI</topic><topic>ISOMERIC NUCLEI</topic><topic>ISOMERIC TRANSITION ISOTOPES</topic><topic>ISOTOPES</topic><topic>Muscle Contraction - drug effects</topic><topic>NUCLEI</topic><topic>ODD-EVEN NUCLEI</topic><topic>ORGANIC ACIDS</topic><topic>ORGANIC COMPOUNDS</topic><topic>Organotechnetium Compounds</topic><topic>PATIENTS</topic><topic>RADIOISOTOPE SCANNING</topic><topic>RADIOISOTOPES</topic><topic>RADIOLOGY AND NUCLEAR MEDICINE</topic><topic>Radionuclide Imaging</topic><topic>SCINTISCANNING</topic><topic>Technetium</topic><topic>TECHNETIUM 99</topic><topic>TECHNETIUM ISOTOPES</topic><topic>ULTRASONOGRAPHY</topic><topic>YEARS LIVING RADIOISOTOPES</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Davis, GB</creatorcontrib><creatorcontrib>Berk, RN</creatorcontrib><creatorcontrib>Scheible, FW</creatorcontrib><creatorcontrib>Witztum, KF</creatorcontrib><creatorcontrib>Gilmore, IT</creatorcontrib><creatorcontrib>Strong, RM</creatorcontrib><creatorcontrib>Hofmann, AF</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>OSTI.GOV</collection><jtitle>AJR, Am. J. Roentgenol.; (United States)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Davis, GB</au><au>Berk, RN</au><au>Scheible, FW</au><au>Witztum, KF</au><au>Gilmore, IT</au><au>Strong, RM</au><au>Hofmann, AF</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Cholecystokinin cholecystography, sonography, and scintigraphy: detection of chronic acalculous cholecystitis</atitle><jtitle>AJR, Am. J. Roentgenol.; (United States)</jtitle><addtitle>AJR Am J Roentgenol</addtitle><date>1982-12</date><risdate>1982</risdate><volume>139</volume><issue>6</issue><spage>1117</spage><epage>1121</epage><pages>1117-1121</pages><issn>0361-803X</issn><eissn>1546-3141</eissn><abstract>Because the efficacy of cholecystokinin cholecystography in the detection of chronic acalculous cholecystitis remains in doubt, the procedure is rarely used in clinical practice. However, the ability to observe gallbladder contraction with sonography and 99mTc-para-isopropylacetanilido-iminodiacetic acid cholescintigraphy (PIPIDA) offers a possibility to improve the sensitivity of the test. To determine if the degree of gallbladder contraction after cholecystokinin is the same as measured by the three techniques and if it differs in symptomatic patients compared to the normal population, cholecystokinin cholecystography, cholecystokinin sonography, and cholecystokinin PIPIDA were performed in 10 symptomatic patients and 10 normal volunteers. The mean maximum contraction of the gallbladder during the three studies was 63%, 61%, and 68%, respectively, for the volunteers, and 72%, 63%, and 73%, respectively, for the patients. The mean maximum gallbladder contraction during all three procedures was 64% +/- 26% SD in the volunteers and 74% +/- 17% SD in the patients. The differences were not statistically significant. Although there was good correlation in the degree of maximum gallbladder contraction among cholecystokinin cholecystography, cholecystokinin sonography, and cholecystokinin PIPIDA, marked variation in both the volunteers and the patients makes it unlikely that the degree of contraction as observed by any of these techniques can be used to indicate the presence of chronic acalculous cholecystitis.</abstract><cop>United States</cop><pub>Am Roentgen Ray Soc</pub><pmid>6983255</pmid><doi>10.2214/ajr.139.6.1117</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record> |
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source | American Roentgen Ray Society; MEDLINE; Alma/SFX Local Collection |
subjects | 550601 - Medicine- Unsealed Radionuclides in Diagnostics 550602 - Medicine- External Radiation in Diagnostics- (1980-) AMINO ACIDS BETA DECAY RADIOISOTOPES BETA-MINUS DECAY RADIOISOTOPES Biliary Dyskinesia - diagnosis BILIARY TRACT CARBOXYLIC ACIDS CHELATING AGENTS Cholecystectomy Cholecystitis - diagnosis Cholecystitis - pathology Cholecystitis - surgery Cholecystography Cholecystokinin - pharmacology CONTRACTION COUNTING TECHNIQUES DIAGNOSIS DIAGNOSTIC TECHNIQUES DIGESTIVE SYSTEM DIGESTIVE SYSTEM DISEASES DISEASES Follow-Up Studies Gallbladder - diagnostic imaging Gallbladder - drug effects HOURS LIVING RADIOISOTOPES Humans Imino Acids INTERMEDIATE MASS NUCLEI ISOMERIC NUCLEI ISOMERIC TRANSITION ISOTOPES ISOTOPES Muscle Contraction - drug effects NUCLEI ODD-EVEN NUCLEI ORGANIC ACIDS ORGANIC COMPOUNDS Organotechnetium Compounds PATIENTS RADIOISOTOPE SCANNING RADIOISOTOPES RADIOLOGY AND NUCLEAR MEDICINE Radionuclide Imaging SCINTISCANNING Technetium TECHNETIUM 99 TECHNETIUM ISOTOPES ULTRASONOGRAPHY YEARS LIVING RADIOISOTOPES |
title | Cholecystokinin cholecystography, sonography, and scintigraphy: detection of chronic acalculous cholecystitis |
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