The sheep growth hormone receptor: Molecular cloning and ontogeny of mRNA expression in the liver

Two overlapping cDNA clones encoding the sheep growth hormone (GH) receptor were isolated from a sheep liver cDNA library. The translated amino acid sequence predicts a polypeptide precursor of 634 amino acids with a calculated molecular weight of 70,799. The mature GH receptor comprises an extracel...

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Veröffentlicht in:	Molecular and cellular endocrinology 1990-10, Vol.73 (2), p.135-145
Hauptverfasser:	Adams, Timothy E., Baker, Louise, Fiddes, Rodney J., Brandon, Malcolm R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Animals Animals, Newborn - metabolism Base Sequence Biological and medical sciences Cloning DNA - genetics Fundamental and applied biological sciences. Psychology Gene Expression Regulation Genes Growth Hormone - metabolism Growth hormone receptor Hormones and neuropeptides. Regulation Humans Hypothalamus. Hypophysis. Epiphysis. Urophysis Liver - growth & development Liver - metabolism Molecular Sequence Data mRNA expression Poly A - analysis Protein Precursors - genetics Rabbits Rats Receptors, Somatotropin - biosynthesis Receptors, Somatotropin - genetics RNA Splicing RNA, Messenger - analysis RNA, Messenger - biosynthesis Sequence Homology, Nucleic Acid Sheep Sheep - genetics Sheep - growth & development Sheep - metabolism Species Specificity Vertebrates: endocrinology
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