Prognostic role of inducible ventricular tachycardia in patients with dilated cardiomyopathy and asymptomatic nonsustained ventricular tachycardia
We studied the prognostic relevance of inducible ventricular tachycardia in 32 patients with dilated cardiomyopathy and spontaneous nonsustained asymptomatic ventricular tachycardia. Programmed ventricular stimulation included basic drive cycle lengths of 600, 500, 430, 370, 330 and 300 msec at sing...
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| Veröffentlicht in: | International journal of cardiology 1990-11, Vol.29 (2), p.215-220 |
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| container_title | International journal of cardiology |
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| creator | Gössinger, Heinz D. Jung, Michael Wagner, Ludwig Stain, Christoph Siostrzonek, Peter Schwarzinger, Ilse Mösslacher, Herbert |
| description | We studied the prognostic relevance of inducible ventricular tachycardia in 32 patients with dilated cardiomyopathy and spontaneous nonsustained asymptomatic ventricular tachycardia. Programmed ventricular stimulation included basic drive cycle lengths of 600, 500, 430, 370, 330 and 300 msec at single, double, and triple extrastimuli. Ventricular tachycardia (⩾ 6 beats) was initiated in 7 patients (22%), with sustained monomorphic ventricular tachycardia being seen in 4 of them. During median follow-up of 21 months (13–44), 14 patients died. Sudden cardiac death occurred in two of the seven patients with inducible tachycardia and in only one of the 25 patients in whom it was not possible to induce tachycardia. Although patients with inducible tachycardia did not differ clinically from those in whom tachycardia could not be induced, the projected mean survival time was significantly shorter in those with inducible tachycardia (10 months vs. 32 months,
P = 0.04). For late sudden cardiac death, the positive predictive value of inducible tachycardia was 28%. The negative predictive value was 96%. We conclude that induction of ventricular tachycardia by programmed stimulation might indicate poorer prognosis in patients with dilated cardiomyopathy. |
| doi_str_mv | 10.1016/0167-5273(90)90224-S |
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P = 0.04). For late sudden cardiac death, the positive predictive value of inducible tachycardia was 28%. The negative predictive value was 96%. We conclude that induction of ventricular tachycardia by programmed stimulation might indicate poorer prognosis in patients with dilated cardiomyopathy.</description><identifier>ISSN: 0167-5273</identifier><identifier>EISSN: 1874-1754</identifier><identifier>DOI: 10.1016/0167-5273(90)90224-S</identifier><identifier>PMID: 2269540</identifier><identifier>CODEN: IJCDD5</identifier><language>eng</language><publisher>Shannon: Elsevier Ireland Ltd</publisher><subject>Adult ; Aged ; Biological and medical sciences ; Cardiology. Vascular system ; Cardiomyopathy, Dilated - mortality ; Cardiomyopathy, Dilated - physiopathology ; Death, Sudden - etiology ; Dilated cardiomyopathy ; Female ; Heart ; Heart Rate ; Humans ; Male ; Medical sciences ; Middle Aged ; Myocarditis. Cardiomyopathies ; Prognosis ; Programmed stimulation ; Prospective Studies ; Sudden cardiac death ; Survival Rate ; Tachycardia - complications ; Tachycardia - physiopathology ; Ventricular Function, Left - physiology ; Ventricular tachycardia</subject><ispartof>International journal of cardiology, 1990-11, Vol.29 (2), p.215-220</ispartof><rights>1990</rights><rights>1991 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c387t-295a5e1840db28bf55252b2dfcedfede000d7d16fa6cfb7f604e425f428dbf443</citedby><cites>FETCH-LOGICAL-c387t-295a5e1840db28bf55252b2dfcedfede000d7d16fa6cfb7f604e425f428dbf443</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/016752739090224S$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=19360645$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/2269540$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Gössinger, Heinz D.</creatorcontrib><creatorcontrib>Jung, Michael</creatorcontrib><creatorcontrib>Wagner, Ludwig</creatorcontrib><creatorcontrib>Stain, Christoph</creatorcontrib><creatorcontrib>Siostrzonek, Peter</creatorcontrib><creatorcontrib>Schwarzinger, Ilse</creatorcontrib><creatorcontrib>Mösslacher, Herbert</creatorcontrib><title>Prognostic role of inducible ventricular tachycardia in patients with dilated cardiomyopathy and asymptomatic nonsustained ventricular tachycardia</title><title>International journal of cardiology</title><addtitle>Int J Cardiol</addtitle><description>We studied the prognostic relevance of inducible ventricular tachycardia in 32 patients with dilated cardiomyopathy and spontaneous nonsustained asymptomatic ventricular tachycardia. Programmed ventricular stimulation included basic drive cycle lengths of 600, 500, 430, 370, 330 and 300 msec at single, double, and triple extrastimuli. Ventricular tachycardia (⩾ 6 beats) was initiated in 7 patients (22%), with sustained monomorphic ventricular tachycardia being seen in 4 of them. During median follow-up of 21 months (13–44), 14 patients died. Sudden cardiac death occurred in two of the seven patients with inducible tachycardia and in only one of the 25 patients in whom it was not possible to induce tachycardia. Although patients with inducible tachycardia did not differ clinically from those in whom tachycardia could not be induced, the projected mean survival time was significantly shorter in those with inducible tachycardia (10 months vs. 32 months,
P = 0.04). For late sudden cardiac death, the positive predictive value of inducible tachycardia was 28%. The negative predictive value was 96%. We conclude that induction of ventricular tachycardia by programmed stimulation might indicate poorer prognosis in patients with dilated cardiomyopathy.</description><subject>Adult</subject><subject>Aged</subject><subject>Biological and medical sciences</subject><subject>Cardiology. Vascular system</subject><subject>Cardiomyopathy, Dilated - mortality</subject><subject>Cardiomyopathy, Dilated - physiopathology</subject><subject>Death, Sudden - etiology</subject><subject>Dilated cardiomyopathy</subject><subject>Female</subject><subject>Heart</subject><subject>Heart Rate</subject><subject>Humans</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Myocarditis. Cardiomyopathies</subject><subject>Prognosis</subject><subject>Programmed stimulation</subject><subject>Prospective Studies</subject><subject>Sudden cardiac death</subject><subject>Survival Rate</subject><subject>Tachycardia - complications</subject><subject>Tachycardia - physiopathology</subject><subject>Ventricular Function, Left - physiology</subject><subject>Ventricular tachycardia</subject><issn>0167-5273</issn><issn>1874-1754</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1990</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kc-KFDEQxoMo67j6Bgq5KHpoTWeS7s5lQRb_wYLC6jlUJxUn0p2MSXqlX8MnNrMzrCc9hBC-X32V-oqQpy173bK2e1NP30jeb18q9koxzkVzfY9s2qEXTdtLcZ9s7pCH5FHOPxhjQqnhjJxx3ikp2Ib8_pLi9xBz8YamOCGNjvpgF-PH-rjBUJI3ywSJFjC71UCyHipB91B8VTP95cuOWj9BQUtv9Tivscq7lUKwFPI670uc4dAixJCXXMCHCv_D_TF54GDK-OR0n5Nv7999vfzYXH3-8Ony7VVjtkNfGq4kSGwHwezIh9FJySUfuXUGrUOLdVjb27Zz0Bk39q5jAgWXTvDBjk6I7Tl5cfTdp_hzwVz07LPBaYKAccl6YJxx1bMKiiNoUsw5odP75GdIq26ZPqxCH3LWh5y1Yvp2Ffq6lj07-S_jjPau6JR91Z-fdMgGJpcgGJ__eqttxzohK3dx5LCGceMx6Wxq9HVMn9AUbaP__0f-AKgBqxM</recordid><startdate>19901101</startdate><enddate>19901101</enddate><creator>Gössinger, Heinz D.</creator><creator>Jung, Michael</creator><creator>Wagner, Ludwig</creator><creator>Stain, Christoph</creator><creator>Siostrzonek, Peter</creator><creator>Schwarzinger, Ilse</creator><creator>Mösslacher, Herbert</creator><general>Elsevier Ireland Ltd</general><general>Elsevier Science</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19901101</creationdate><title>Prognostic role of inducible ventricular tachycardia in patients with dilated cardiomyopathy and asymptomatic nonsustained ventricular tachycardia</title><author>Gössinger, Heinz D. ; Jung, Michael ; Wagner, Ludwig ; Stain, Christoph ; Siostrzonek, Peter ; Schwarzinger, Ilse ; Mösslacher, Herbert</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c387t-295a5e1840db28bf55252b2dfcedfede000d7d16fa6cfb7f604e425f428dbf443</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1990</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Biological and medical sciences</topic><topic>Cardiology. Vascular system</topic><topic>Cardiomyopathy, Dilated - mortality</topic><topic>Cardiomyopathy, Dilated - physiopathology</topic><topic>Death, Sudden - etiology</topic><topic>Dilated cardiomyopathy</topic><topic>Female</topic><topic>Heart</topic><topic>Heart Rate</topic><topic>Humans</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Myocarditis. Cardiomyopathies</topic><topic>Prognosis</topic><topic>Programmed stimulation</topic><topic>Prospective Studies</topic><topic>Sudden cardiac death</topic><topic>Survival Rate</topic><topic>Tachycardia - complications</topic><topic>Tachycardia - physiopathology</topic><topic>Ventricular Function, Left - physiology</topic><topic>Ventricular tachycardia</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Gössinger, Heinz D.</creatorcontrib><creatorcontrib>Jung, Michael</creatorcontrib><creatorcontrib>Wagner, Ludwig</creatorcontrib><creatorcontrib>Stain, Christoph</creatorcontrib><creatorcontrib>Siostrzonek, Peter</creatorcontrib><creatorcontrib>Schwarzinger, Ilse</creatorcontrib><creatorcontrib>Mösslacher, Herbert</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>International journal of cardiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Gössinger, Heinz D.</au><au>Jung, Michael</au><au>Wagner, Ludwig</au><au>Stain, Christoph</au><au>Siostrzonek, Peter</au><au>Schwarzinger, Ilse</au><au>Mösslacher, Herbert</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Prognostic role of inducible ventricular tachycardia in patients with dilated cardiomyopathy and asymptomatic nonsustained ventricular tachycardia</atitle><jtitle>International journal of cardiology</jtitle><addtitle>Int J Cardiol</addtitle><date>1990-11-01</date><risdate>1990</risdate><volume>29</volume><issue>2</issue><spage>215</spage><epage>220</epage><pages>215-220</pages><issn>0167-5273</issn><eissn>1874-1754</eissn><coden>IJCDD5</coden><abstract>We studied the prognostic relevance of inducible ventricular tachycardia in 32 patients with dilated cardiomyopathy and spontaneous nonsustained asymptomatic ventricular tachycardia. Programmed ventricular stimulation included basic drive cycle lengths of 600, 500, 430, 370, 330 and 300 msec at single, double, and triple extrastimuli. Ventricular tachycardia (⩾ 6 beats) was initiated in 7 patients (22%), with sustained monomorphic ventricular tachycardia being seen in 4 of them. During median follow-up of 21 months (13–44), 14 patients died. Sudden cardiac death occurred in two of the seven patients with inducible tachycardia and in only one of the 25 patients in whom it was not possible to induce tachycardia. Although patients with inducible tachycardia did not differ clinically from those in whom tachycardia could not be induced, the projected mean survival time was significantly shorter in those with inducible tachycardia (10 months vs. 32 months,
P = 0.04). For late sudden cardiac death, the positive predictive value of inducible tachycardia was 28%. The negative predictive value was 96%. We conclude that induction of ventricular tachycardia by programmed stimulation might indicate poorer prognosis in patients with dilated cardiomyopathy.</abstract><cop>Shannon</cop><pub>Elsevier Ireland Ltd</pub><pmid>2269540</pmid><doi>10.1016/0167-5273(90)90224-S</doi><tpages>6</tpages></addata></record> |
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| subjects | Adult Aged Biological and medical sciences Cardiology. Vascular system Cardiomyopathy, Dilated - mortality Cardiomyopathy, Dilated - physiopathology Death, Sudden - etiology Dilated cardiomyopathy Female Heart Heart Rate Humans Male Medical sciences Middle Aged Myocarditis. Cardiomyopathies Prognosis Programmed stimulation Prospective Studies Sudden cardiac death Survival Rate Tachycardia - complications Tachycardia - physiopathology Ventricular Function, Left - physiology Ventricular tachycardia |
| title | Prognostic role of inducible ventricular tachycardia in patients with dilated cardiomyopathy and asymptomatic nonsustained ventricular tachycardia |
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