Measurements of antifungal levels in corneal tissue : a simplified bioassay for amphotericin B

Measuring precise antifungal levels in the cornea with broth-dilution bioassays is difficult, as standard techniques involving visual determination of endpoints are hindered by corneal debris. To increase the precision of the measurement, we modified the sample preparation for bioassay of rabbit cor...

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Veröffentlicht in:	Graefe's archive for clinical and experimental ophthalmology 1990-01, Vol.228 (6), p.538-540
Hauptverfasser:	WILLIAMS, T. E, O'DAY, D. M, STEVEN HEAD, W, ROBINSON, R. D
Format:	Artikel
Sprache:	eng
Schlagworte:	Amphotericin B - analysis Amphotericin B - pharmacokinetics Animals Antibiotics. Antiinfectious agents. Antiparasitic agents Antifungal agents Biological and medical sciences Biological Assay - methods Candida albicans - drug effects Conjunctiva - metabolism Cornea - metabolism Medical sciences Pharmacology. Drug treatments Rabbits Random Allocation
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