Tumor necrosis factor induces contraction of mesangial cells and alters their cytoskeletons

Tumor necrosis factor induces contraction of mesangial cells and alters their cytoskeletons. Cultures of human mesangial cells (MC) were established from the renal cortex of surgical specimen. The characteristic spindle-shaped or stellate appearance of MC was altered after treatment with tumor necro...

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Veröffentlicht in:	Kidney international 1990-11, Vol.38 (5), p.795-802
Hauptverfasser:	Camussi, Giovanni, Turello, Ernesto, Tetta, Ciro, Bussolino, Federico, Baglioni, Corrado
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Cell physiology Cells, Cultured Cytoskeleton - drug effects Fundamental and applied biological sciences. Psychology Glomerular Mesangium - cytology Glomerular Mesangium - drug effects Humans In Vitro Techniques Microscopy, Fluorescence Microscopy, Phase-Contrast Molecular and cellular biology Platelet Activating Factor - pharmacology Platelet Activating Factor - physiology Responses to growth factors, tumor promotors, other factors Time Factors Tumor Necrosis Factor-alpha - pharmacology
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