The influence of chronic treatment with verapamil on plasma atrial natriuretic peptide levels in young elderly hypertensive patients

In a double-blind, placebo-controlled cross-over study, the plasma atrial natriuretic peptide (ANP) levels of nine young and ten elderly hypertensive patients were compared after placebo and after treatment with 120 mg verapamil given three times daily over 4 weeks. During placebo, plasma ANP levels...

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Veröffentlicht in:European journal of clinical pharmacology 1990-01, Vol.39 (1), p.S39-S40
Hauptverfasser: VAN BORTEL, L. M. A. B, SCHIFFERS, P. M. H, BÖHM, R. O. B, MOOIJ, J. M. V, RAHN, K. H, STRUYKER-BOUDIER, H. A. J
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container_title European journal of clinical pharmacology
container_volume 39
creator VAN BORTEL, L. M. A. B
SCHIFFERS, P. M. H
BÖHM, R. O. B
MOOIJ, J. M. V
RAHN, K. H
STRUYKER-BOUDIER, H. A. J
description In a double-blind, placebo-controlled cross-over study, the plasma atrial natriuretic peptide (ANP) levels of nine young and ten elderly hypertensive patients were compared after placebo and after treatment with 120 mg verapamil given three times daily over 4 weeks. During placebo, plasma ANP levels proved to be higher in elderly patients than in young subjects. Chronic treatment with verapamil induced a rise in ANP levels in both young and elderly patients with hypertension.
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Chronic treatment with verapamil induced a rise in ANP levels in both young and elderly patients with hypertension.</abstract><cop>Heidelberg</cop><cop>Berlin</cop><pub>Springer</pub><pmid>2148150</pmid><doi>10.1007/BF01409206</doi></addata></record>
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subjects Adult
Aged
Antihypertensive agents
Atrial Natriuretic Factor - blood
Biological and medical sciences
Blood Pressure - drug effects
Cardiovascular system
Double-Blind Method
Humans
Hypertension - blood
Hypertension - drug therapy
Medical sciences
Middle Aged
Pharmacology. Drug treatments
Time Factors
Verapamil - administration & dosage
Verapamil - therapeutic use
title The influence of chronic treatment with verapamil on plasma atrial natriuretic peptide levels in young elderly hypertensive patients
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