CD109 represents a novel branch of the alpha2-macroglobulin/complement gene family

We report here the genomic organization and phylogenic relationships of CD109, a member of the the alpha2-macroglobulin/complement (AMCOM) gene family. CD109 is a GPI-linked glycoprotein expressed on endothelial cells, platelets, activated T-cells, and a wide variety of tumors. We cloned full-length...

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Veröffentlicht in:	Gene 2004-03, Vol.327 (2), p.171-183
Hauptverfasser:	Solomon, Keith R, Sharma, Parul, Chan, Melvin, Morrison, Paul T, Finberg, Robert W
Format:	Artikel
Sprache:	eng
Schlagworte:	alpha-Macroglobulins - genetics Amino Acid Sequence Animals Antigens, CD - chemistry Antigens, CD - genetics Antigens, CD - metabolism Cell Line, Tumor CHO Cells Chromosome Mapping Cloning, Molecular Complement System Proteins - genetics Cricetinae DNA, Complementary - chemistry DNA, Complementary - genetics Evolution, Molecular Exons Genes - genetics GPI-Linked Proteins Humans Introns Molecular Sequence Data Multigene Family - genetics Neoplasm Proteins Phosphatidylinositol Diacylglycerol-Lyase - metabolism Phylogeny Reverse Transcriptase Polymerase Chain Reaction Sequence Alignment Sequence Analysis, DNA Sequence Analysis, Protein Sequence Homology, Amino Acid
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