Entry of pseudorabies virus into CHO cells is blocked at the level of penetration

Replication of pseudorabies virus (PrV) in Chinese hamster ovary (CHO) cells, a cell line naturally resistant to infection by herpesviruses, is blocked at the level of penetration. Virions bound to the surface of CHO cells are taken up into cytoplasmic vesicles and degraded.

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Bibliographische Detailangaben
Veröffentlicht in:	Archives of virology 1990-01, Vol.115 (3/4), p.309-316
Hauptverfasser:	Sawitzky, D, Hampl, H, Habermehl, K.O
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals binding Biological and medical sciences Cell Adhesion Cell Line - microbiology Cell Line - ultrastructure cell lines Cell Membrane - microbiology cell surface attachment Cricetinae Cricetulus Cytoplasm - microbiology disease resistance Fundamental and applied biological sciences. Psychology Heparin - pharmacology Herpesvirus 1, Suid - physiology Herpesvirus 1, Suid - ultrastructure Membrane Fusion Microbiology pseudorabies virus replication Replicative cycle, interference, host-virus relations, pathogenicity, miscellaneous strains Suid herpesvirus 1 surfaces Virology Virus Replication - drug effects
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Beschreibung
Zusammenfassung:	Replication of pseudorabies virus (PrV) in Chinese hamster ovary (CHO) cells, a cell line naturally resistant to infection by herpesviruses, is blocked at the level of penetration. Virions bound to the surface of CHO cells are taken up into cytoplasmic vesicles and degraded.
ISSN:	0304-8608 1432-8798
DOI:	10.1007/BF01310539