Successful Use of Levosimendan in a Patient with Peripartum Cardiomyopathy

This case represents the first reported use of levosimendan, a calcium-sensitizing drug with additional vasodilation properties, for treatment of a woman with peripartum cardiomyopathy. Levosimendan induced a steady decline of increased pulmonary capillary wedge pressure, followed by a definitive in...

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Veröffentlicht in:Anesthesia and analgesia 2004-03, Vol.98 (3), p.822-824
Hauptverfasser: Benlolo, Sidney, Lefoll, Cécile, Katchatouryan, Vahan, Payen, Didier, Mebazaa, Alexandre
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container_end_page 824
container_issue 3
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container_title Anesthesia and analgesia
container_volume 98
creator Benlolo, Sidney
Lefoll, Cécile
Katchatouryan, Vahan
Payen, Didier
Mebazaa, Alexandre
description This case represents the first reported use of levosimendan, a calcium-sensitizing drug with additional vasodilation properties, for treatment of a woman with peripartum cardiomyopathy. Levosimendan induced a steady decline of increased pulmonary capillary wedge pressure, followed by a definitive increase in cardiac stroke volume. The patient recovered from this serious episode of heart failure, and she ultimately regained left ventricular function.
doi_str_mv 10.1213/01.ANE.0000099717.40471.83
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source MEDLINE; Journals@Ovid LWW Legacy Archive; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Journals@Ovid Complete
subjects Adult
Anesthesia
Anesthesia, Obstetrical
Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy
Apnea - etiology
Apnea - physiopathology
Biological and medical sciences
Cardiomyopathies - drug therapy
Female
Hemodynamics - drug effects
Hemodynamics - physiology
Humans
Hydrazones - therapeutic use
Medical sciences
Pregnancy
Pregnancy Complications, Cardiovascular - drug therapy
Pyridazines - therapeutic use
Simendan
Vasodilator Agents - therapeutic use
title Successful Use of Levosimendan in a Patient with Peripartum Cardiomyopathy
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