Monotherapy with pefloxacin in multidrug-resistant nosocomial Gram-negative bacteraemia

Twenty patients who developed nosocomial Gram-negative bacteraemias in the medical or surgical intensive care units were treated with pefloxacin. All organisms were susceptible to pefloxacin and had not responded to previous antimicrobial therapy. The bacteraemias were eradicated in 16 of the 20 pat...

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Veröffentlicht in:	Journal of antimicrobial chemotherapy 1990, Vol.26 (suppl-B), p.91-95
Hauptverfasser:	Limson, B. M., Peña, A. C., Garvez, M. D.
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Oral Adult Aged Antibacterial agents Antibiotics. Antiinfectious agents. Antiparasitic agents Biological and medical sciences Cross Infection - drug therapy Drug Resistance, Microbial Female Humans Infusions, Intravenous Male Medical sciences Middle Aged Pefloxacin - administration & dosage Pefloxacin - therapeutic use Pharmacology. Drug treatments Pneumonia - complications Pseudomonas Infections - complications Pseudomonas Infections - drug therapy Sepsis - complications Sepsis - drug therapy
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Zusammenfassung:	Twenty patients who developed nosocomial Gram-negative bacteraemias in the medical or surgical intensive care units were treated with pefloxacin. All organisms were susceptible to pefloxacin and had not responded to previous antimicrobial therapy. The bacteraemias were eradicated in 16 of the 20 patients, all of whom tolerated the therapy without adverse effects.
ISSN:	0305-7453 1460-2091
DOI:	10.1093/jac/26.suppl_B.91