The effect of individual HLA-A and -B mismatches on the generation of cytotoxic T lymphocyte precursors

In order to study the correlation between HLA mismatches and the cytotoxic T lymphocyte precursor frequency, we used a limiting dilution analysis to determine the CTLp frequencies against individual mismatched HLA-A and -B alloantigens in 21 patients waiting for a renal transplant. Altogether, thirt...

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Veröffentlicht in:	Transplantation 1990-12, Vol.50 (6), p.1008-1010
Hauptverfasser:	ZHANG, L, VAN BREE, S, VAN ROOD, J. J, CLAAS, F. H. J
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Biological and medical sciences Bone marrow, stem cells transplantation. Graft versus host reaction Child Female Graft Rejection Hematopoietic Stem Cells - immunology HLA-A Antigens - immunology HLA-B Antigens - immunology Humans Kidney Transplantation Male Medical sciences Middle Aged T-Lymphocytes, Cytotoxic - immunology Transfusions. Complications. Transfusion reactions. Cell and gene therapy
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