Intrahepatic B cell clonal expansions and extrahepatic manifestations of chronic HCV infection

B cell repertoire in three biological compartments (liver, bone marrow and peripheral blood) of 30 unselected patients chronically infected with HCV has been characterized. Restriction of humoral immune response defined by enrichment of B cell clonal expansions occurred in the liver of 15 patients (...

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Veröffentlicht in:European journal of immunology 2004-01, Vol.34 (1), p.126-136
Hauptverfasser: Sansonno, Domenico, Lauletta, Gianfranco, De Re, Valli, Tucci, Felicia Anna, Gatti, Pietro, Racanelli, Vito, Boiocchi, Mauro, Dammacco, Franco
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Sprache:eng
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