Bifunctional effects of transforming growth factor-β (TGF-β) on endothelial cell growth correlate with phenotypes of TGF-β binding sites

Transforming growth factor-β (TGF-β) is a bifunctional, dose-dependent regulator of endothelial cell proliferation induced in vitro by heparin-binding growth factor 1 (HBGF-1, acidic FGF). Here we have examined the relationship between endothelial cell growth and the expression of cell surface bindi...

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Veröffentlicht in:	Experimental cell research 1990-12, Vol.191 (2), p.299-304
Hauptverfasser:	Myoken, Yoshinari, Kan, Mikio, Sato, Gordon H., McKeehan, Wallace L., Sato, J.Denry
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Binding Sites - drug effects Binding Sites - physiology Biological and medical sciences Cattle Cell Division - drug effects Cell Division - physiology Cell physiology Dose-Response Relationship, Drug Endothelium, Vascular - cytology Endothelium, Vascular - drug effects Endothelium, Vascular - ultrastructure Fibroblast Growth Factor 1 - metabolism Fundamental and applied biological sciences. Psychology Molecular and cellular biology Myocardium - cytology Myocardium - metabolism Myocardium - ultrastructure Phenotype Receptors, Cell Surface - genetics Receptors, Cell Surface - metabolism Receptors, Fibroblast Growth Factor Receptors, Mitogen - metabolism Receptors, Transforming Growth Factor beta Receptors, Vascular Endothelial Growth Factor Responses to growth factors, tumor promotors, other factors Transforming Growth Factor beta - metabolism Transforming Growth Factor beta - pharmacology Transforming Growth Factor beta - physiology
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