Myeloid ELF1-like Factor Is a Potent Activator of Interleukin-8 Expression in Hematopoietic Cells

Myeloid ELF1-like factor (MEF), also known as ELF4, is a member of the ETS family of transcription factors which is expressed in hematopoietic cells. MEF-deficient mice have defects in natural killer cell and natural killer T cell development, suggesting a role for MEF in regulating innate immunity....

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Veröffentlicht in:	The Journal of biological chemistry 2004-02, Vol.279 (8), p.6395-6400
Hauptverfasser:	Hedvat, Cyrus V., Yao, JinJuan, Sokolic, Robert A., Nimer, Stephen D.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals COS Cells DNA, Complementary - metabolism DNA-Binding Proteins - metabolism Gene Expression Regulation Genes, Reporter Hematopoietic Stem Cells - metabolism Humans Interleukin-8 - biosynthesis Interleukin-8 - metabolism Luciferases - metabolism myeloid ELF1-like factor Neutrophils - metabolism Oligonucleotide Array Sequence Analysis Plasmids - metabolism Promoter Regions, Genetic Protein Binding Reverse Transcriptase Polymerase Chain Reaction RNA Interference RNA, Small Interfering - metabolism Time Factors Transcription Factors - metabolism
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