Effects of fig latex on lipid peroxidation and CCl4-induced lipid peroxidation in rat liver
The oral and intraperitoneal effects of fig milk latex on lipid peroxidation and CCl4-induced lipid peroxidation in liver homogenates of female rats were investigated. Oral treatment had no effect, while i.p. administration produced a significant increase in hepatic lipid peroxidation. When the late...
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| Veröffentlicht in: | Journal of ethnopharmacology 1990-09, Vol.30 (2), p.215-221 |
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| container_title | Journal of ethnopharmacology |
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| creator | Al-Bayati, Z.A.F Alwan, A.H |
| description | The oral and intraperitoneal effects of fig milk latex on lipid peroxidation and CCl4-induced lipid peroxidation in liver homogenates of female rats were investigated. Oral treatment had no effect, while i.p. administration produced a significant increase in hepatic lipid peroxidation. When the latex was given before CCl4 treatment; it produced no protective effect against CCl4-induced hepatotoxicity. Addition of the latex to the incubation mixture produced a dose-dependent increase in lipid autoxidation, while the chloroform and ether extracts of the latex, as well as heated latex, had no effect on hepatic lipid autoxidation. |
| doi_str_mv | 10.1016/0378-8741(90)90010-Q |
| format | Article |
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Oral treatment had no effect, while i.p. administration produced a significant increase in hepatic lipid peroxidation. When the latex was given before CCl4 treatment; it produced no protective effect against CCl4-induced hepatotoxicity. Addition of the latex to the incubation mixture produced a dose-dependent increase in lipid autoxidation, while the chloroform and ether extracts of the latex, as well as heated latex, had no effect on hepatic lipid autoxidation.</description><identifier>ISSN: 0378-8741</identifier><identifier>EISSN: 1872-7573</identifier><identifier>DOI: 10.1016/0378-8741(90)90010-Q</identifier><identifier>PMID: 2255212</identifier><language>eng</language><publisher>Ireland</publisher><subject>Administration, Oral ; Animals ; carbon tetrachloride ; Carbon Tetrachloride - pharmacology ; females ; Ficus carica ; Injections, Intraperitoneal ; latex ; Latex - administration & dosage ; Latex - pharmacology ; lipid peroxidation ; Lipid Peroxidation - drug effects ; Liver - drug effects ; Liver - metabolism ; Male ; Malondialdehyde - metabolism ; Rats ; Rats, Inbred Strains</subject><ispartof>Journal of ethnopharmacology, 1990-09, Vol.30 (2), p.215-221</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c326t-a7c1da1c09c3a6c9ef9b4007fd1d3b8e81d380b3281d1eba1b052d678ced02073</citedby><cites>FETCH-LOGICAL-c326t-a7c1da1c09c3a6c9ef9b4007fd1d3b8e81d380b3281d1eba1b052d678ced02073</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/2255212$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Al-Bayati, Z.A.F</creatorcontrib><creatorcontrib>Alwan, A.H</creatorcontrib><title>Effects of fig latex on lipid peroxidation and CCl4-induced lipid peroxidation in rat liver</title><title>Journal of ethnopharmacology</title><addtitle>J Ethnopharmacol</addtitle><description>The oral and intraperitoneal effects of fig milk latex on lipid peroxidation and CCl4-induced lipid peroxidation in liver homogenates of female rats were investigated. Oral treatment had no effect, while i.p. administration produced a significant increase in hepatic lipid peroxidation. When the latex was given before CCl4 treatment; it produced no protective effect against CCl4-induced hepatotoxicity. Addition of the latex to the incubation mixture produced a dose-dependent increase in lipid autoxidation, while the chloroform and ether extracts of the latex, as well as heated latex, had no effect on hepatic lipid autoxidation.</description><subject>Administration, Oral</subject><subject>Animals</subject><subject>carbon tetrachloride</subject><subject>Carbon Tetrachloride - pharmacology</subject><subject>females</subject><subject>Ficus carica</subject><subject>Injections, Intraperitoneal</subject><subject>latex</subject><subject>Latex - administration & dosage</subject><subject>Latex - pharmacology</subject><subject>lipid peroxidation</subject><subject>Lipid Peroxidation - drug effects</subject><subject>Liver - drug effects</subject><subject>Liver - metabolism</subject><subject>Male</subject><subject>Malondialdehyde - metabolism</subject><subject>Rats</subject><subject>Rats, Inbred Strains</subject><issn>0378-8741</issn><issn>1872-7573</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1990</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNptkM1LAzEQxYMoWqv_geKeRA-rM8nuJnuUUj9AEFFPHkI2HyWy3a3JVup_b2qLJ09vmPfmMfwIOUG4QsDqGhgXueAFXtRwWQMg5M87ZISC05yXnO2S0V_kgBzG-AEAHAvYJ_uUliVFOiLvU-esHmLWu8z5Wdaqwa6yvstav_AmW9jQr7xRg08r1ZlsMmmL3Hdmqa35L-O7LKghOV82HJE9p9poj7c6Jm-309fJff74dPcwuXnMNaPVkCuu0SjUUGumKl1bVzdF-tQZNKwRViQR0DCaBrSNwgZKaiou0gtAgbMxOd_0LkL_ubRxkHMftW1b1dl-GaVItLAsRAoWm6AOfYzBOrkIfq7Ct0SQa6ZyDUyugcka5C9T-ZzOTrf9y2Zuzd_RFmLyzza-U71Us-CjfHuhgAyQFxUUnP0An3J7UA</recordid><startdate>19900901</startdate><enddate>19900901</enddate><creator>Al-Bayati, Z.A.F</creator><creator>Alwan, A.H</creator><scope>FBQ</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19900901</creationdate><title>Effects of fig latex on lipid peroxidation and CCl4-induced lipid peroxidation in rat liver</title><author>Al-Bayati, Z.A.F ; Alwan, A.H</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c326t-a7c1da1c09c3a6c9ef9b4007fd1d3b8e81d380b3281d1eba1b052d678ced02073</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1990</creationdate><topic>Administration, Oral</topic><topic>Animals</topic><topic>carbon tetrachloride</topic><topic>Carbon Tetrachloride - pharmacology</topic><topic>females</topic><topic>Ficus carica</topic><topic>Injections, Intraperitoneal</topic><topic>latex</topic><topic>Latex - administration & dosage</topic><topic>Latex - pharmacology</topic><topic>lipid peroxidation</topic><topic>Lipid Peroxidation - drug effects</topic><topic>Liver - drug effects</topic><topic>Liver - metabolism</topic><topic>Male</topic><topic>Malondialdehyde - metabolism</topic><topic>Rats</topic><topic>Rats, Inbred Strains</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Al-Bayati, Z.A.F</creatorcontrib><creatorcontrib>Alwan, A.H</creatorcontrib><collection>AGRIS</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of ethnopharmacology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Al-Bayati, Z.A.F</au><au>Alwan, A.H</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Effects of fig latex on lipid peroxidation and CCl4-induced lipid peroxidation in rat liver</atitle><jtitle>Journal of ethnopharmacology</jtitle><addtitle>J Ethnopharmacol</addtitle><date>1990-09-01</date><risdate>1990</risdate><volume>30</volume><issue>2</issue><spage>215</spage><epage>221</epage><pages>215-221</pages><issn>0378-8741</issn><eissn>1872-7573</eissn><abstract>The oral and intraperitoneal effects of fig milk latex on lipid peroxidation and CCl4-induced lipid peroxidation in liver homogenates of female rats were investigated. Oral treatment had no effect, while i.p. administration produced a significant increase in hepatic lipid peroxidation. When the latex was given before CCl4 treatment; it produced no protective effect against CCl4-induced hepatotoxicity. Addition of the latex to the incubation mixture produced a dose-dependent increase in lipid autoxidation, while the chloroform and ether extracts of the latex, as well as heated latex, had no effect on hepatic lipid autoxidation.</abstract><cop>Ireland</cop><pmid>2255212</pmid><doi>10.1016/0378-8741(90)90010-Q</doi><tpages>7</tpages></addata></record> |
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| ispartof | Journal of ethnopharmacology, 1990-09, Vol.30 (2), p.215-221 |
| issn | 0378-8741 1872-7573 |
| language | eng |
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| source | MEDLINE; Elsevier ScienceDirect Journals Complete |
| subjects | Administration, Oral Animals carbon tetrachloride Carbon Tetrachloride - pharmacology females Ficus carica Injections, Intraperitoneal latex Latex - administration & dosage Latex - pharmacology lipid peroxidation Lipid Peroxidation - drug effects Liver - drug effects Liver - metabolism Male Malondialdehyde - metabolism Rats Rats, Inbred Strains |
| title | Effects of fig latex on lipid peroxidation and CCl4-induced lipid peroxidation in rat liver |
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