The role of investigations for term stillbirths
The aim of the study was to document the role of laboratory investigations for unexpected stillbirths at term. It was a retrospective casenote review of 75 unexpected stillbirths at term from 1995 to 1999, at the National Maternity Hospital, Dublin, Republic of Ireland. Investigations performed incl...
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| Veröffentlicht in: | Journal of obstetrics and gynaecology 2004-02, Vol.24 (2), p.133-134 |
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| container_title | Journal of obstetrics and gynaecology |
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| creator | Bohra, U Regan, C O'Connell, MP Geary, MP Kelehan, P Keane, DP |
| description | The aim of the study was to document the role of laboratory investigations for unexpected stillbirths at term. It was a retrospective casenote review of 75 unexpected stillbirths at term from 1995 to 1999, at the National Maternity Hospital, Dublin, Republic of Ireland.
Investigations performed included blood tests, chromosomal analysis, autopsy and placental histology. Perinatal autopsy was the most informative investigation with positive findings in 49% of cases. There were positive placental findings in 37% of cases. Six of the 26 cases showed abnormal karyotyping. Of the blood tests performed, the Kleihauer - Betke test was most informative, revealing a feto-maternal haemorrhage in 8% of cases and anticardiolipin antibodies were positive in 4% of cases. FBC, TORCH and glycosylated Hb were negative in all 75 patients. Despite thorough investigations 32 of cases (43%) remained unexplained. |
| doi_str_mv | 10.1080/01443610410001645398 |
| format | Article |
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Investigations performed included blood tests, chromosomal analysis, autopsy and placental histology. Perinatal autopsy was the most informative investigation with positive findings in 49% of cases. There were positive placental findings in 37% of cases. Six of the 26 cases showed abnormal karyotyping. Of the blood tests performed, the Kleihauer - Betke test was most informative, revealing a feto-maternal haemorrhage in 8% of cases and anticardiolipin antibodies were positive in 4% of cases. FBC, TORCH and glycosylated Hb were negative in all 75 patients. Despite thorough investigations 32 of cases (43%) remained unexplained.</description><identifier>ISSN: 0144-3615</identifier><identifier>EISSN: 1364-6893</identifier><identifier>DOI: 10.1080/01443610410001645398</identifier><identifier>PMID: 14766446</identifier><identifier>CODEN: JOGYDW</identifier><language>eng</language><publisher>England: Informa UK Ltd</publisher><subject>Adolescent ; Adult ; Autopsy ; Diagnostic Techniques, Obstetrical and Gynecological ; Female ; Hematologic Tests ; Humans ; Investigations ; Karyotyping ; Obstetrics ; Placenta - pathology ; Pregnancy ; Pregnancy Outcome ; Retrospective Studies ; Stillbirth</subject><ispartof>Journal of obstetrics and gynaecology, 2004-02, Vol.24 (2), p.133-134</ispartof><rights>2004 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted 2004</rights><rights>Copyright Carfax Publishing Company Feb 2004</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c356t-80053c7b0bbdcb8b3bf9efa4c0250fd7ae7b763ab4a86fed588917e65c8e73933</citedby><cites>FETCH-LOGICAL-c356t-80053c7b0bbdcb8b3bf9efa4c0250fd7ae7b763ab4a86fed588917e65c8e73933</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.tandfonline.com/doi/pdf/10.1080/01443610410001645398$$EPDF$$P50$$Ginformaworld$$H</linktopdf><linktohtml>$$Uhttps://www.tandfonline.com/doi/full/10.1080/01443610410001645398$$EHTML$$P50$$Ginformaworld$$H</linktohtml><link.rule.ids>314,780,784,27924,27925,59647,60436,61221,61402</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/14766446$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Bohra, U</creatorcontrib><creatorcontrib>Regan, C</creatorcontrib><creatorcontrib>O'Connell, MP</creatorcontrib><creatorcontrib>Geary, MP</creatorcontrib><creatorcontrib>Kelehan, P</creatorcontrib><creatorcontrib>Keane, DP</creatorcontrib><title>The role of investigations for term stillbirths</title><title>Journal of obstetrics and gynaecology</title><addtitle>J Obstet Gynaecol</addtitle><description>The aim of the study was to document the role of laboratory investigations for unexpected stillbirths at term. It was a retrospective casenote review of 75 unexpected stillbirths at term from 1995 to 1999, at the National Maternity Hospital, Dublin, Republic of Ireland.
Investigations performed included blood tests, chromosomal analysis, autopsy and placental histology. Perinatal autopsy was the most informative investigation with positive findings in 49% of cases. There were positive placental findings in 37% of cases. Six of the 26 cases showed abnormal karyotyping. Of the blood tests performed, the Kleihauer - Betke test was most informative, revealing a feto-maternal haemorrhage in 8% of cases and anticardiolipin antibodies were positive in 4% of cases. FBC, TORCH and glycosylated Hb were negative in all 75 patients. Despite thorough investigations 32 of cases (43%) remained unexplained.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Autopsy</subject><subject>Diagnostic Techniques, Obstetrical and Gynecological</subject><subject>Female</subject><subject>Hematologic Tests</subject><subject>Humans</subject><subject>Investigations</subject><subject>Karyotyping</subject><subject>Obstetrics</subject><subject>Placenta - pathology</subject><subject>Pregnancy</subject><subject>Pregnancy Outcome</subject><subject>Retrospective Studies</subject><subject>Stillbirth</subject><issn>0144-3615</issn><issn>1364-6893</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2004</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkEtLAzEUhYMotlb_gcjgwt3Ym-YxmY0i4gsEN7oOSSaxI5lJTaaK_96UFkQRXV24fOfcew5ChxhOMQiYAqaUcAwUAwDmlJFabKExJpyWXNRkG41XSJkZNkJ7Kb2sOGB0F40wrTinlI_R9HFuixi8LYIr2v7NpqF9VkMb-lS4EIvBxq7IO-91G4d52kc7TvlkDzZzgp6urx4vb8v7h5u7y4v70hDGh1IAMGIqDVo3RgtNtKutU9TAjIFrKmUrXXGiNFWCO9swIWpcWc6MsBWpCZmgk7XvIobXZf5Kdm0y1nvV27BMUuTIADORweMf4EtYxj7_JmeYVZjVlGeIriETQ0rROrmIbafih8QgV23K39rMsqON91J3tvkSberLwPkaaPtcVqfeQ_SNHNSHD9FF1Zs2SfLPibNvDnOr_DA3KtqvHH8afAIeXJTf</recordid><startdate>200402</startdate><enddate>200402</enddate><creator>Bohra, U</creator><creator>Regan, C</creator><creator>O'Connell, MP</creator><creator>Geary, MP</creator><creator>Kelehan, P</creator><creator>Keane, DP</creator><general>Informa UK Ltd</general><general>Taylor & Francis</general><general>Taylor & Francis Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>K9.</scope><scope>7X8</scope></search><sort><creationdate>200402</creationdate><title>The role of investigations for term stillbirths</title><author>Bohra, U ; Regan, C ; O'Connell, MP ; Geary, MP ; Kelehan, P ; Keane, DP</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c356t-80053c7b0bbdcb8b3bf9efa4c0250fd7ae7b763ab4a86fed588917e65c8e73933</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2004</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Autopsy</topic><topic>Diagnostic Techniques, Obstetrical and Gynecological</topic><topic>Female</topic><topic>Hematologic Tests</topic><topic>Humans</topic><topic>Investigations</topic><topic>Karyotyping</topic><topic>Obstetrics</topic><topic>Placenta - pathology</topic><topic>Pregnancy</topic><topic>Pregnancy Outcome</topic><topic>Retrospective Studies</topic><topic>Stillbirth</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Bohra, U</creatorcontrib><creatorcontrib>Regan, C</creatorcontrib><creatorcontrib>O'Connell, MP</creatorcontrib><creatorcontrib>Geary, MP</creatorcontrib><creatorcontrib>Kelehan, P</creatorcontrib><creatorcontrib>Keane, DP</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of obstetrics and gynaecology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Bohra, U</au><au>Regan, C</au><au>O'Connell, MP</au><au>Geary, MP</au><au>Kelehan, P</au><au>Keane, DP</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The role of investigations for term stillbirths</atitle><jtitle>Journal of obstetrics and gynaecology</jtitle><addtitle>J Obstet Gynaecol</addtitle><date>2004-02</date><risdate>2004</risdate><volume>24</volume><issue>2</issue><spage>133</spage><epage>134</epage><pages>133-134</pages><issn>0144-3615</issn><eissn>1364-6893</eissn><coden>JOGYDW</coden><abstract>The aim of the study was to document the role of laboratory investigations for unexpected stillbirths at term. It was a retrospective casenote review of 75 unexpected stillbirths at term from 1995 to 1999, at the National Maternity Hospital, Dublin, Republic of Ireland.
Investigations performed included blood tests, chromosomal analysis, autopsy and placental histology. Perinatal autopsy was the most informative investigation with positive findings in 49% of cases. There were positive placental findings in 37% of cases. Six of the 26 cases showed abnormal karyotyping. Of the blood tests performed, the Kleihauer - Betke test was most informative, revealing a feto-maternal haemorrhage in 8% of cases and anticardiolipin antibodies were positive in 4% of cases. FBC, TORCH and glycosylated Hb were negative in all 75 patients. Despite thorough investigations 32 of cases (43%) remained unexplained.</abstract><cop>England</cop><pub>Informa UK Ltd</pub><pmid>14766446</pmid><doi>10.1080/01443610410001645398</doi><tpages>2</tpages></addata></record> |
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| identifier | ISSN: 0144-3615 |
| ispartof | Journal of obstetrics and gynaecology, 2004-02, Vol.24 (2), p.133-134 |
| issn | 0144-3615 1364-6893 |
| language | eng |
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| source | MEDLINE; Taylor & Francis:Master (3349 titles) |
| subjects | Adolescent Adult Autopsy Diagnostic Techniques, Obstetrical and Gynecological Female Hematologic Tests Humans Investigations Karyotyping Obstetrics Placenta - pathology Pregnancy Pregnancy Outcome Retrospective Studies Stillbirth |
| title | The role of investigations for term stillbirths |
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