Chiral Separation of Deprenyl-N-Oxide Isomers by Capillary Electrophoresis Using Various Cyclodextrin Derivatives

Chiral separation of deprenyl-N-oxide isomers is presented using capillary electrophoresis in the presence of various cyclodextrin (CD) derivatives. This recently identified metabolite of R-(−)-deprenyl may possess desirable pharmacological activities. The effect of the cavity size and the substitue...

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Veröffentlicht in:	Journal of chromatographic science 2004-01, Vol.42 (1), p.21-26
Hauptverfasser:	Tábi, Tamás, Halász, Attila Sándor, Pálfi, Melinda, Magyar, Kálmán, Szökő, Éva
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Biological and medical sciences Cyclodextrins - chemistry Electrophoresis, Capillary - methods General pharmacology Isomerism Medical sciences Monoamine Oxidase Inhibitors - chemistry Pharmacology. Drug treatments Selegiline - analogs & derivatives Selegiline - chemistry Selegiline - isolation & purification Stereoisomerism
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