Role of systemic therapy in advanced non-small-cell lung cancer
Increasing evidence supports the investigation of chemotherapy in patients with non-small-cell lung cancer (NSCLC). Randomized studies in patients with stage IV disease have shown increased survival in chemotherapy-treated patients compared to best supportive care and indicate the ability of chemoth...
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| Veröffentlicht in: | The American Journal of Medicine 1990-12, Vol.89 (6), p.777-786 |
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| container_issue | 6 |
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| container_title | The American Journal of Medicine |
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| creator | Vokes, Everett E. Vijayakumar, Srinivasan Bitran, Jacob D. Hoffman, Philip C. Golomb, Harvey M. |
| description | Increasing evidence supports the investigation of chemotherapy in patients with non-small-cell lung cancer (NSCLC). Randomized studies in patients with stage IV disease have shown increased survival in chemotherapy-treated patients compared to best supportive care and indicate the ability of chemotherapy to alter the natural history of this disease. Randomized studies involving adjuvant and neoadjuvant chemotherapy have also shown encouraging results. These studies and results of recent pilot studies utilizing neoadjuvant chemotherapy and concomitant chemoradiotherapy indicate a potential benefit from the use of chemotherapy in patients with NSCLC and call for its continued intensive investigation in clinical trials. |
| doi_str_mv | 10.1016/0002-9343(90)90221-X |
| format | Article |
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These studies and results of recent pilot studies utilizing neoadjuvant chemotherapy and concomitant chemoradiotherapy indicate a potential benefit from the use of chemotherapy in patients with NSCLC and call for its continued intensive investigation in clinical trials.</description><subject>Antineoplastic Combined Chemotherapy Protocols - therapeutic use</subject><subject>Carcinoma, Non-Small-Cell Lung - drug therapy</subject><subject>Combined Modality Therapy</subject><subject>Humans</subject><subject>Lung Neoplasms - drug therapy</subject><subject>Neoplasm Staging</subject><issn>0002-9343</issn><issn>1555-7162</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1990</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kE1LAzEQhoMoWqv_QGFPoodokk3S3YsixS8oCKLQW0iTiUb2oya7hf57s7b06GkY3nfemXkQOqPkmhIqbwghDJc5zy9LclUSxiie76ERFULgCZVsH412liN0HON3akkp5CE6ZHTCJZcjdPfWVpC1Lovr2EHtTdZ9QdDLdeabTNuVbgzYrGkbHGtdVdhAVWVV33xmZpDCCTpwuopwuq1j9PH48D59xrPXp5fp_QwbLliHC0mltIxwmheCCBA6lyXPLZXWLUrpLBGC5wVzE05FqotFOjA96YAK55JzjC42ucvQ_vQQO1X7OByjG2j7qApCRZESkpFvjCa0MQZwahl8rcNaUaIGbmqAogYoqiTqj5uap7HzbX6_qMHuhragkn670SE9ufIQVDQeBjg-gOmUbf3_C34BaIZ6Ig</recordid><startdate>19901201</startdate><enddate>19901201</enddate><creator>Vokes, Everett E.</creator><creator>Vijayakumar, Srinivasan</creator><creator>Bitran, Jacob D.</creator><creator>Hoffman, Philip C.</creator><creator>Golomb, Harvey M.</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19901201</creationdate><title>Role of systemic therapy in advanced non-small-cell lung cancer</title><author>Vokes, Everett E. ; Vijayakumar, Srinivasan ; Bitran, Jacob D. ; Hoffman, Philip C. ; Golomb, Harvey M.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c452t-86166d204138505e5a36943d16dfb96fd0554382f7415382bb174016fe15ff943</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1990</creationdate><topic>Antineoplastic Combined Chemotherapy Protocols - therapeutic use</topic><topic>Carcinoma, Non-Small-Cell Lung - drug therapy</topic><topic>Combined Modality Therapy</topic><topic>Humans</topic><topic>Lung Neoplasms - drug therapy</topic><topic>Neoplasm Staging</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Vokes, Everett E.</creatorcontrib><creatorcontrib>Vijayakumar, Srinivasan</creatorcontrib><creatorcontrib>Bitran, Jacob D.</creatorcontrib><creatorcontrib>Hoffman, Philip C.</creatorcontrib><creatorcontrib>Golomb, Harvey M.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>The American Journal of Medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Vokes, Everett E.</au><au>Vijayakumar, Srinivasan</au><au>Bitran, Jacob D.</au><au>Hoffman, Philip C.</au><au>Golomb, Harvey M.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Role of systemic therapy in advanced non-small-cell lung cancer</atitle><jtitle>The American Journal of Medicine</jtitle><addtitle>Am J Med</addtitle><date>1990-12-01</date><risdate>1990</risdate><volume>89</volume><issue>6</issue><spage>777</spage><epage>786</epage><pages>777-786</pages><issn>0002-9343</issn><eissn>1555-7162</eissn><abstract>Increasing evidence supports the investigation of chemotherapy in patients with non-small-cell lung cancer (NSCLC). 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| ispartof | The American Journal of Medicine, 1990-12, Vol.89 (6), p.777-786 |
| issn | 0002-9343 1555-7162 |
| language | eng |
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| source | MEDLINE; ScienceDirect Journals (5 years ago - present) |
| subjects | Antineoplastic Combined Chemotherapy Protocols - therapeutic use Carcinoma, Non-Small-Cell Lung - drug therapy Combined Modality Therapy Humans Lung Neoplasms - drug therapy Neoplasm Staging |
| title | Role of systemic therapy in advanced non-small-cell lung cancer |
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