Expression and activity analyses of CTLA4 in peripheral blood lymphocytes in systemic lupus erythematosus patients

The objective of this study was to determine the expression and activity of CTLA4 in T-cells of systemic lupus erythematosus (SLE) patients. Expression of CTLA4 on freshly isolated peripheral blood T-cells was evaluated in 33 SLE patients and 25 controls using flow cytometry.The T-cells from 19 SLE...

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Veröffentlicht in:	Lupus 2004-01, Vol.13 (1), p.24-31
Hauptverfasser:	Hirashima, M, Fukazawa, T, Abe, K, Morita, Y, Kusaoi, M, Hashimoto, H
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Antibodies, Monoclonal - analysis Antigens, CD Antigens, Differentiation - immunology Antigens, Differentiation - metabolism B7-1 Antigen - immunology B7-1 Antigen - metabolism CD28 Antigens - immunology CD28 Antigens - metabolism CTLA-4 Antigen Female Flow Cytometry Fluorescent Antibody Technique Humans Lupus Erythematosus, Systemic - immunology Lupus Erythematosus, Systemic - metabolism Lymphocyte Activation Male Middle Aged T-Lymphocytes - immunology T-Lymphocytes - metabolism
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