Assays for measuring in vitro basophil activation induced by recombinant allergens

The diagnosis of type I allergy is essentially based on clinical data, skin tests, and measurements of allergen-specific IgE. However, the determination of specific IgE per se does not permit a definitive conclusion concerning the response of effector cells to the respective allergen(s) and consecut...

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Veröffentlicht in:	Methods (San Diego, Calif.) Calif.), 2004-03, Vol.32 (3), p.265-270
Hauptverfasser:	Valent, Peter, Hauswirth, Alexander W., Natter, Susanne, Sperr, Wolfgang R., Bühring, Hans-Jörg, Valenta, Rudolf
Format:	Artikel
Sprache:	eng
Schlagworte:	Allergens - immunology Allergy Antigens, CD - immunology Basophils - immunology Basophils - metabolism CD203c CD63 Clinical Laboratory Techniques Histamine Histamine - metabolism Hypersensitivity, Immediate - diagnosis Hypersensitivity, Immediate - immunology IgE IgE-receptor Immunoassay - methods Immunoglobulin E - immunology In Vitro Techniques Platelet Membrane Glycoproteins - immunology Recombinant Proteins - immunology Tetraspanin 30
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