Influence of short-term dietary weight loss on cortisol secretion and metabolism in obese men

OBJECTIVES: Obesity is associated with increased inactivation of cortisol by hepatic A-ring 5alpha- and 5beta-reductases, impaired hepatic regeneration of cortisol from cortisone by 11beta-hydroxysteroid dehydrogenase type 1 (11HSD1), but increased subcutaneous adipose 11HSD1 activity enhancing loca...

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Veröffentlicht in:	European journal of endocrinology 2004-02, Vol.150 (2), p.185-194
Hauptverfasser:	Johnstone, AM, Faber, P, Andrew, R, Gibney, ER, Elia, M, Lobley, G, Stubbs, RJ, Walker, BR
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Biological and medical sciences Body Composition - physiology Caloric Restriction Clinical Studies Endocrinopathies Fundamental and applied biological sciences. Psychology Humans Hydrocortisone - blood Hydrocortisone - metabolism Hydrocortisone - urine Male Medical sciences Metabolic diseases Middle Aged Obesity Obesity - diet therapy Obesity - metabolism Starvation - metabolism Vertebrates: endocrinology Weight Loss - physiology
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