Is a presymptomatic malignant hyperthermia in-vitro diagnosis with 4-chloro-3-ethyl phenol possible? A study using porcine skeletal preparations

The diagnosis of malignant hyperthermia is currently performed with the in-vitro contracture test (IVCT) with halothane and caffeine. This test has a sensitivity of 99.0 % but only a specificity of 93.6 %. A cumulative IVCT with 4-chloro-3-ethyl-phenole (CEP) has recently been shown to differentiate...

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Veröffentlicht in:	Anästhesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS, 2004-02, Vol.39 (2), p.81-86
Hauptverfasser:	Gerbershagen, M U, Wappler, F, Fiege, M, Weisshorn, R, Kolodzie, K, Schulte am Esch, J
Format:	Artikel
Sprache:	ger
Schlagworte:	Animals Chlorophenols In Vitro Techniques Malignant Hyperthermia - diagnosis Muscle Contraction - drug effects Muscle, Skeletal - drug effects Swine
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