Stomach-brain communication by vagal afferents in response to luminal acid backdiffusion, gastrin, and gastric acid secretion

Vagal afferents play a role in gut-brain signaling of physiological and pathological stimuli. Here, we investigated how backdiffusion of luminal HCl or NH(4)OH and pentagastrin-stimulated acid secretion interact in the communication between rat stomach and brain stem. Rats were pretreated intraperit...

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Veröffentlicht in:	American journal of physiology: Gastrointestinal and liver physiology 2004-03, Vol.286 (3), p.G403-G411
Hauptverfasser:	Danzer, Marion, Jocic, Milana, Samberger, Claudia, Painsipp, Evelin, Bock, Elisabeth, Pabst, Maria-Anna, Crailsheim, Karl, Schicho, Rudolf, Lippe, Irmgard T, Holzer, Peter
Format:	Artikel
Sprache:	eng
Schlagworte:	Afferent Pathways - physiology Ammonia - pharmacology Animals Anti-Ulcer Agents - pharmacology Autoradiography Brain - physiology Brain Stem - physiology Diffusion Female Gastric Acid - secretion Gastrins - secretion Gastrointestinal Motility - physiology Gene Expression - drug effects Genes, fos - genetics In Situ Hybridization Male Neurons - physiology Pentagastrin - pharmacology Pressure Rats Rats, Sprague-Dawley Receptors, Cholecystokinin - antagonists & inhibitors Receptors, Cholecystokinin - metabolism RNA, Messenger - biosynthesis Sex Characteristics Solitary Nucleus - metabolism Spinal Cord - physiology Stomach - physiology Vagus Nerve - physiology
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