Demonstration of functional role of TECK/CCL25 in T lymphocyte-endothelium interaction in inflamed and uninflamed intestinal mucosa

It has recently been suggested that C-C chemokines may play a role in the organ-specific homing of lymphocytes, but there is not enough in vivo evidence in intestinal mucosa. The aim of this study was to examine whether thymus-expressed chemokine (TECK)/CCL25 and its ligand CCR9 are involved in T-ly...

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Veröffentlicht in:	American journal of physiology: Gastrointestinal and liver physiology 2004-03, Vol.286 (3), p.G458-G466
Hauptverfasser:	Hosoe, Naoki, Miura, Soichiro, Watanabe, Chikako, Tsuzuki, Yoshikazu, Hokari, Ryota, Oyama, Tokushige, Fujiyama, Yoichi, Nagata, Hiroshi, Ishii, Hiromasa
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Blotting, Western Cell Movement - physiology Chemokines, CC - physiology Colon - metabolism Colon - pathology Endothelium - metabolism Endothelium - physiology Enteritis - metabolism Enteritis - pathology Epithelium - pathology Female Flow Cytometry Immunohistochemistry Intestinal Mucosa - cytology Intestinal Mucosa - metabolism Intestinal Mucosa - pathology Intestine, Small - metabolism Intestine, Small - pathology Mice Mice, Inbred BALB C Microscopy, Fluorescence Receptors, CCR Receptors, Cell Surface - metabolism Receptors, Chemokine - physiology Reverse Transcriptase Polymerase Chain Reaction T-Lymphocytes - physiology Tumor Necrosis Factor-alpha - biosynthesis
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