Regulation of ATP-Binding Cassette Transporter A1 Transcription by Thyroid Hormone Receptor

Transcriptional regulation of the ATP-binding cassette transporter (ABCA1) gene is complex. It involves multiple transcription start sites and the binding of several different transcription factors to the ABCA1 promoter region. Cholesterol- and oxysterol-mediated up-regulation of ABCA1 transcription...

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Veröffentlicht in:	Biochemistry (Easton) 2004-02, Vol.43 (6), p.1626-1632
Hauptverfasser:	Huuskonen, Jarkko, Vishnu, Meeta, Pullinger, Clive R, Fielding, Phoebe E, Fielding, Christopher J
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals ATP Binding Cassette Transporter 1 ATP-Binding Cassette Transporters - antagonists & inhibitors ATP-Binding Cassette Transporters - genetics ATP-Binding Cassette Transporters - metabolism Binding, Competitive - physiology Cell Extracts - genetics Cell Extracts - immunology Cell Line Cells, Cultured Chickens Chromatin - metabolism DNA-Binding Proteins - immunology DNA-Binding Proteins - metabolism Electrophoretic Mobility Shift Assay Fibroblasts - immunology Fibroblasts - metabolism Humans Liver X Receptors Nuclear Proteins - immunology Nuclear Proteins - metabolism Orphan Nuclear Receptors Precipitin Tests Receptors, Cytoplasmic and Nuclear - biosynthesis Receptors, Cytoplasmic and Nuclear - genetics Receptors, Cytoplasmic and Nuclear - physiology Receptors, Thyroid Hormone - biosynthesis Receptors, Thyroid Hormone - physiology Repetitive Sequences, Nucleic Acid Repressor Proteins - biosynthesis Repressor Proteins - physiology Transcription, Genetic - physiology Transfection
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