Dual role of sequence-dependent DNA curvature in nucleosome stability: the critical test of highly bent Crithidia fasciculata DNA tract

In spite of the knowledge of the nucleosome molecular structure, the role of DNA intrinsic curvature in determining nucleosome stabilization is still an open question. In this paper, we describe a general model that allows the prediction of the nucleosome stability, tested on 83 different DNA sequen...

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Veröffentlicht in:	Biophysical chemistry 2004-01, Vol.107 (1), p.7-17
Hauptverfasser:	Scipioni, Anita, Pisano, Sabrina, Anselmi, Claudio, Savino, Maria, De Santis, Pasquale
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Base Sequence Crithidia fasciculata - genetics DNA, Protozoan - chemistry Models, Genetic Molecular Sequence Data Nucleic Acid Conformation Nucleosomes - chemistry Nucleosomes - ultrastructure Thermodynamics
Online-Zugang:	Volltext
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