Genetic Predisposition for Adult Lactose Intolerance and Relation to Diet, Bone Density, and Bone Fractures

Evidence that genetic disposition for adult lactose intolerance significantly affects calcium intake, bone density, and fractures in postmenopausal women is presented. PCR‐based genotyping of lactase gene polymorphisms may complement diagnostic procedures to identify persons at risk for both lactose...

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Veröffentlicht in:	Journal of bone and mineral research 2004-01, Vol.19 (1), p.42-47
Hauptverfasser:	Obermayer‐Pietsch, Barbara M, Bonelli, Christine M, Walter, Daniela E, Kuhn, Regina J, Fahrleitner‐Pammer, Astrid, Berghold, Andrea, Goessler, Walter, Stepan, Vinzenz, Dobnig, Harald, Leb, Georg, Renner, Wilfried
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Factors Aged aging Animals Biological and medical sciences Bone Density bone fractures bone mineral density Calcifediol - blood calcium absorption Calcium, Dietary - administration & dosage Calcium, Dietary - metabolism Collagen - blood Diet epidemiology Female Femur Neck - chemistry Fractures, Bone - complications Fundamental and applied biological sciences. Psychology gene association Gene Frequency Genetic Predisposition to Disease - genetics Genotype Humans Intestinal Absorption Lactase-Phlorizin Hydrolase - genetics lactose intolerance Lactose Intolerance - complications Lactose Intolerance - genetics Lumbar Vertebrae - chemistry menopause Middle Aged Milk nutrition Osteocalcin - blood osteoporosis Pelvic Bones - chemistry Peptide Fragments - blood Polymorphism, Genetic - genetics polymorphisms Postmenopause - blood Postmenopause - genetics Postmenopause - metabolism Regression Analysis Skeleton and joints Vertebrates: osteoarticular system, musculoskeletal system Yogurt
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